The Vespiary

The Hive => Methods Discourse => Topic started by: roger2003 on August 16, 2003, 05:42:00 AM

Title: Benzylcyanide
Post by: roger2003 on August 16, 2003, 05:42:00 AM

Benzylcyanide was prepared in the vapour phase (430 – 450° C) from benzylamine and formic acid (or an ester) over silica gel. Yield about 42%
Unreactet benzylamine is recovered for the next run.

Patent DE482943 (http://l2.espacenet.com/dips/viewer?PN=DE482943&CY=gb&LG=en&DB=EPD)

Title: Does it seem useful to you?
Post by: Rhodium on August 16, 2003, 05:45:00 AM

I'd classify any reaction running at 400°C+ as very impractical, especially one involving cyanides.