magnesium organometallicderivative of 1,5-dibromopentane
gives PCP. The only difficulty in this route is the preparation of
the dibromopentane Grignard reagent,
Reaction of N-benzoylpiperidine with the lithium or magnesium
organometallic derivative of 1,5-dibromopentane gives PCP. The only difficulty in this route
is the preparation of the dibromopentane Grignard reagent, with its strict requirement for
anhydrous conditions (Method
?).