If solubility of substance X is known in solvent A and in solvent B, and A and B are
not miscible, can one simply calculate somehow how much will go into either when one has a container with a certain percentage of A and B? Does this go in a linear manner or are partitioning coefficients always determined empirically?
Couldn't find any info on this...
I'm wondering because of this example: GBL is known to be miscible with water and most organic solvents (e.g. DCM). Yet, I have seen more than one paper where GBL is extracted from water solution with a very small amount of DCM. So what makes GBL prefer DCM instead of H2O? Can such behaviour be predicted or even calculated in any way?
Thanks a lot in advance!