Author Topic: BROMO SAFROLE  (Read 3030 times)

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Vibrating_Lights

  • Guest
BROMO SAFROLE
« on: June 10, 2003, 11:01:00 AM »
Is ity possible to hydrolize Bromosafrole to MdP2POL With
NaOH Heat and H2O?
VL_


hypo

  • Guest
probably.
« Reply #1 on: June 10, 2003, 12:19:00 PM »
to increase reaction speed, you might either work with
an organic solvent/PTC system or in alcoholic solution.
hydrolysis also works in acidic medium (ie. dil. H2SO4).
you'll always get some elimination side-reaction.

now the $100.000-question is: why would you want to do
that? (halo-safrole => MDP2P?)

Vibrating_Lights

  • Guest
Bromine Month
« Reply #2 on: June 10, 2003, 01:27:00 PM »
It is national bromine month.


hypo

  • Guest
gee..
« Reply #3 on: June 10, 2003, 02:18:00 PM »
thanks for your cooperation  :P

Rhodium

  • Guest
bromosafrole won't give much mdp2pol
« Reply #4 on: June 10, 2003, 02:20:00 PM »
That reaction sounds like you are going to get isosafrole as your major product (elimination instead of substitution).

https://www.thevespiary.org/rhodium/Rhodium/chemistry/halide.carbonyl.html

is much better, and if you really want MDP2Pol, reduce the product from this reaction.