Hi!
Swim had this idea of making 4-methyl-2,5-dimethoxy-benzaldehyde from 2,5-DMBA, utillizing friedel-craft with methyliodide. Is this possible? Would the groups attatched to the benzene rings direct to the correct position on the ring(as the do with bromine)? If it is possible to do with the BA, how about the corresponding alpha-methylPEA? Swim would think that it would be hard to do with that one, because it is a base and would probably separate from the soln. with the HI formed...
Thanks!
Regards
Peter