In trying to make an chlorinate the OH with Phosphorus oxy chloride will this work the solvents dichloromethane or chloroform in the making of chloroephedrine? As thionyl chloride becomes less available and methods to synthesise are not to friendly , there is a need to find alternatives. I used the search engine and read halfpint version of synthesis and also in the synthesis or LSD, where in the acid chloride step they used this compund,(phosphorous oxy chloride).
So to re-phrase my question will the Phosphorous oxychloride react well in chloroform or dichloromethane as solvent, in the synthesis of the chloroephedrine?.....java
Edited: some editing done to correct some terms