The Vespiary

The Hive => Chemistry Discourse => Topic started by: Vaaguh on October 10, 2002, 05:29:00 PM

Title: 2c-b -> dob ?
Post by: Vaaguh on October 10, 2002, 05:29:00 PM

Do you guys think this would work ?

(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000366927-file_nfh2.jpg)

I am not sure if the Al/Hg will reduce the alkene producing a decent yield, should I consider using NaBH4 and Al/Hg for reducing ?

Title: The dehydration of the intermediate nitroalkohol ...
Post by: Rhodium on October 10, 2002, 05:54:00 PM

The dehydration of the intermediate nitroalkohol to the nitroalkene won't happen without vigorous conditions, such as heating with phtalic anhydride, as the alkene isn't conjugated with the benzene ring. That step alone will be so low-yielding that the synthesis is of no use.

Start from scratch, that is much more plausible than this suggestion.

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Alcohol, an unconsciousness-expanding drug

Title: Even furthermore.
Post by: No1CockSucker on October 13, 2002, 11:54:00 PM

2C-B + potassium permanganate --> 4-bromo-2,5-dimethoxy-benzoic acid.