Author Topic: Novel GHB Synth Idea  (Read 1486 times)

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Disciple

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Novel GHB Synth Idea
« on: November 20, 2002, 02:44:00 AM »
Look i'm a fairly new chem student so take it easy. I'm probably way off track, but how can we got forward without novel idea's. Ok
My Idea is the coupling of ethanol and acetone using an Manganese(III)acetate to form 5-Hydroxy-pentan-2-one which could possibly somehow be made into GHB (doubtful)
or
The coupling of ethanol and acetaldehyde and then the oxidation to GHB

I dunno. but I think it has possibilities
Check these out for more info

Rhodiums site on p2p from benzene and acetone using Mn(III) catalyst
Has good pics showing the mechanism

https://www.thevespiary.org/rhodium/Rhodium/chemistry/p2p.manganese.html



Preparation of Manganese(III)acetate

https://www.thevespiary.org/rhodium/Rhodium/chemistry/manganous.acetate.html