Hailz Master DickAround and ChiefBee!
Not sure of the validity here as it deals with
20g(-)-ephedrine
__> 10g of
(+)-Pseudoephedrine-O-sulfate ester
The question here is could (-)-Pseudoephedrine be esterified in this same way to yield (+)-Pseudoephedrine sulfate?Hell...any way ya figure it, bees will be taking a 50% yield hit
But it would be better to the 50% hit in quantity instead of quality(effectiveness)
Esterification of ephedrine
===========================
(+)-Pseudo-ephedrin-O-sulfuric-acid-ester from (-)-Ephedrin.
Hermann Emde, Helvetica Chimica Acta, p.402 (1929).
To 100 grams of ice-cold concentrated sulfuric acid situated in a beaker,
20 grams of natural (-)-ephedrine hydrochloride is added in about 40 portions
within 10 minutes, whereupon hydrogen chloride gas is vigorously evolved.
The solution is shaken under cooling with ice until all solids has dissolved.
The walls of the beaker is rinsed from any residual crystals with 10 ml conc.
H2SO4, the beaker is removed from the ice, and left to stand at 15 deg C for
15 minutes, whereupon the contents of the beaker is poured upon 200 grams of
crushed ice in a 500 ml beaker, which also is cooled from the outside with
an ice-bath. 300 ml of absolute ethanol is now added, whereby beautiful white
crystal needles of (+)-Pseudoephedrine-O-sulfate ester precipitates.
The crystals are filtered with suction in a small Buchner funnel, washed with
a little cold water, and after air drying the yield is approximately 10g of
(+)-Pseudoephedrine-O-sulfate ester.
http://www.ephedra.demon.nl/stories/chemical_ref.htm