The Vespiary

The Hive => Chemicals & Equipment => Topic started by: Belial on November 06, 2003, 11:29:00 AM

Title: BDO in Australia
Post by: Belial on November 06, 2003, 11:29:00 AM
Can anyone confirm that BDO is currently uncontrolled in Australia? What degree of scrutiny is placed upon its ordering? Are scientific companies more scrutinizing in regards to 1-2.5L Orders as compared to industrial orders of 200L?
Title: BDO Stituation
Post by: Belial on December 11, 2003, 11:57:00 AM
Title: Re: BDO in Australia
Post by: chris on January 30, 2015, 09:19:21 AM
I am not sure to be honest but seeing as there is scheduling in UK, Canada etc. I would be very surprised if it was legal.
Title: Re: BDO in Australia
Post by: Vesp on January 30, 2015, 09:59:01 AM
What is BDO in this context?
Title: Re: BDO in Australia
Post by: Polonium on January 30, 2015, 11:56:30 AM
chris: In case you didn't realise this is a 12 year necropost. I'm don't think Belial is still waiting for an answer :)
Title: Re: BDO in Australia
Post by: chris on January 30, 2015, 08:23:34 PM
didn't even look :)
I thought it was,4-Butanediol?
could be wrong
Title: Re: BDO in Australia
Post by: Vesp on January 31, 2015, 12:17:55 AM
Oh yes that's almost certainly what it is, now seeing 1,4-BDO around. 
Title: Re: BDO in Australia
Post by: ricky on March 05, 2016, 12:51:24 AM

1,4-butanediol IS captured by:

the industry-based PACIA Code of Practice for Supply Diversion to Illicit Drug Manufacture (PACIA Code). This Code has been developed in consultation with law enforcement authorities to control supply of certain substances, including 1,4-butanediol now listed as an Illicit Drug Precursor (Category 1). Three Australian states (NSW, QLD and WA) have legislated to make elements of the PACIA Code mandatory and other states are developing regulations.

1,4-butanediol is NOT listed in:

the Hazardous Substances Information System (HSIS), and
the Australian Customs (Prohibited Imports) Regulations which cover the import/export of drugs and certain precursor substances used in the manufacture of illicit drugs. However, GHB (gamma-hydroxbutyrate—see above) is classified as a psychotropic substance and listed as a prohibited import that requires import authorisation.

Of course they will be more suspicious of large orders. A single liter doesn't scream distribution but 200 certainly would. They would most likely think you are trying to make GHB, however BDO can be ingested and gets metabolized to the drug, anyway. I'm not sure which is better or worse but a chemical supplier in another country might not say anything to NICNAS since they don't have to. Then you would need to worry about customs.

All this is rather useless since it's such a simple compound and relatively easy to make, and GBL is even easier. For the latter just do a Sandmeyer reaction with GABA in H2O to turn the amine group into an alcohol. For BDO, the classical approach is acetylene + formaldehyde and then hydrogenate the alkyne, but there have been many recent articles outlining simple bio-synthetic approaches, and one could even use pentoses to get furfural via dehydration then decarbonylation of the aldehyde to furan, and finally hydrolysis to BDO. Here are a bunch of others:

I'm sure about 217 other ways could be found with a bit of creativity. Industrially, people are obviously trying to cut costs as much as they can.