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Xylene vs DCM for MDP2P

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DiMethyl:
One was wondering if xylene could be used in place of DCM for extracting MDP2P from the Benzoquinone Wacker Oxidation of Safrole in Methanol mixture?
Anyone here ever read anything about that?
DiMethyl

ApprenticeCook:
NP solvent requried....

DCM is easier to see from post wacker mix so you can sperate it but any NP will do just as well, make sure you add plenty of NP and agitate, and do several extractions, pool and evap solvent.

-AC

DiMethyl:
Well---there are degrees of polarity and degrees of solubility, so things are never as simple as they may appear on the surface.

DiMethyl

ApprenticeCook:
thats why i said if you dont use DCM make sure you do several more extraction washes than normal, this will be sure to counteract any solubility differnces....

Why did you ask the question if you already knew the answer?

-AC

DiMethyl:
I asked the question because I have never seen posted anywhere anything about the solubility of mdp2p in xylene, and I have looked extensively.
Considering the relative chemistries of the respective molecules, it would seem reasonable that xylene would dissolve the ketone.
But then chemistry is complex and I was looking for perhaps some input from someone with some actual experience with this issue.
DiMethyl

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