The Vespiary

The Hive => Novel Discourse => Topic started by: Barium on January 10, 2003, 02:01:00 PM

Title: Pharmacologically interesting piperazines
Post by: Barium on January 10, 2003, 02:01:00 PM
The piperazine family can, perhaps, be a fertile soil to explore.

Patent US6172229 (http://l2.espacenet.com/dips/viewer?PN=US6172229&CY=gb&LG=en&DB=EPD)



Title: Only if you are interested in neuroleptics...
Post by: Lilienthal on January 10, 2003, 02:59:00 PM
Only if you are interested in neuroleptics...  :)  Or am I missing something?
Title: Considering the dopamine/noradrealine ...
Post by: Barium on January 10, 2003, 03:46:00 PM
Considering the dopamine/noradrealine releasing effect of 1-benzylpiperazine and the wierd serotonergic effect of 1-(3-trifluorophenyl)piperazine, I´m pretty sure there might be a few hidden treasures within the piperazine family.
Also, in the patent above, on page 2, there is also mentioned something about a japanese patent regarding m-trifluoromethylphenyl benzyl piperazines having analgetic and tranqualizing properties. Might come handy when the voices in the head becomes too loud and annoying.  ;)

Title: Barium
Post by: Aurelius on January 10, 2003, 05:34:00 PM
Hey Barium, would you be interested in having that text typed/posted?  don't want to do it if nobody's interested.