The Vespiary

The Hive => Novel Discourse => Topic started by: neuromodulator on March 27, 2002, 06:33:00 PM

Title: Reducing and then brominating Phenylephrine
Post by: neuromodulator on March 27, 2002, 06:33:00 PM
I can get tons of pure phenylephrine HCl powder.  (HI too.) Can I reduce the phenylephrine, then methoxylate it and then brominate it to get something good?  If so, what?  (3-methoxy-4-bromo-phenylethylamine?)
Title: N-methyl-PEA no good
Post by: Rhodium on March 27, 2002, 10:27:00 PM
The compound is 1-(3-hydroxyphenyl)-2-(methylamino)-ethanol. You can only remove the side chain hydroxy group through HI/P reduction (or any other ephedrine -> meth procedure), and even then the product is a N-methyl-phenethylamine, and I know of no such active compounds.