The Vespiary

Structure-Activity Relationships in Cannabinoids
Raj K. Razdan

Pharmacological Reviews Vol. 38, No. 2, 75-149 (1986) (https://www.thevespiary.org/rhodium/Rhodium/djvu/cannabinoid-sar.djvu)

(https://www.thevespiary.org/rhodium/Rhodium/djvu/cannabinoid-sar.djvu)

I. Introduction
II. Drug development: an overview
III. Assessment of biological activity
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)A. Dog ataxia test
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)B. Monkey behavioral test
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)C. Mouse ring immobility assay
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)D. Tetrahydrocannabinol-seizure susceptible (THC-SS) rabbit model
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)E. Spontaneous activity and body temperature in mice
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)F. Drug discrimination procedure
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)G. Conclusions
IV. Structure-activity relationships (SAR)
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)A. SAR in man
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000495536-file_oxgw.gif)B. SAR in animals
V. Conclusion