The Hive => Tryptamine Chemistry => Topic started by: Sektor7G on February 14, 2002, 04:00:00 AM
Title: LSA to LSD ?
Post by: Sektor7G on February 14, 2002, 04:00:00 AM
Ok, i was looking around and found this rxn for LSD. But in a message above the writeup it says tha 10gm of amide from ergot was used. Is it possible to use the amide from morning glory seeds insted?
Dissolve 10 g lysergic acid amide in 200 ml methanolic potassium hydroxide solution.
Remove the methanol by vacuum as soon as the amide is dissolved.
Dissolve the residue which is left into 200 ml of an 8% solution of potassium hydroxide in water.
Heat this mixture on a steam bath for 1 hour.
Pass a steam of nitrogen gas through the flask during the heating process. (The ammonia which is evolved in the gas stream may be titrated with hydrochloric acid in order to follow the reaction.)
Neutralize the mixture with tartaric acid (neutral to congo red) and run it through a filter paper.
Extract the mixture with ether in a separatory funnel. Save the water layer, discard the ether layer.
Filter the solution through a filter paper and evaporate.
Upon evaporation, dry crystals of lysergic acid will be obtained. :)
A clean lab is a happy lab:)
Title: Re: LSA to LSD ?
Post by: hest on February 14, 2002, 09:05:00 AM
------------------------ Is it possible to use the amide from morning glory seeds insted? ------------------------ Yes
Title: Re: LSA to LSD ?
Post by: terbium on February 14, 2002, 06:16:00 PM
Ok, i was looking around and found this rxn for LSD. The procedure that you posted is not for preparing LSD, it is for preparing lysergic acid.
Title: Re: LSA to LSD ?
Post by: Sektor7G on February 14, 2002, 09:07:00 PM
Aww Damn!! Well, i guess its back to the drawing board.:) A clean lab is a happy lab:)
Title: Re: LSA to LSD ?
Post by: amalgum on February 15, 2002, 03:34:00 AM