Hello.
Is going from 4-Hydoxy-Tryptamine into 4-Hydroxy-DiMethylTryptamine possible via any of the routes used to go from tryptamine into dmt? as in this -
https://www.thevespiary.org/rhodium/Rhodium/chemistry/tryptamine2dmt.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/tryptamine2dmt.html)
?
Or is this completly impossible because the link between the HO molecule and the Carbon is too weak and will break when subjected to this kind of synthesis route?
4-Hydoxy-Tryptamine into 4-Hydroxy-Tryptamine
huu ???
But yess, iff you have some 4-OH-tryptamine (lucky bastard) you can use the method in the link.
Post 127141 (https://www.thevespiary.org/talk/index.php?topic=13241.msg12714100#msg12714100)
(ejlmp: "Psilocin in 5 steps", Tryptamine Chemistry)By which method you want to synthesize the 4-hydroxy-indole?
I guess that the one who will choose to follow this reaction would like to purchase the 4-hydroxyindloe from a supplier.
Sorry, 4-hydroxy-tryptamine was meant of course....
Purchasing 4-hydroxy-indole/tryptamine is no good idea (in Lego's opinion) for two reasons:
1) the price
2) it is quite suspicious
Try unsubstituted tryptamine first....
I wonder what would be the effects of 6-ho-DMT if this compound was ever synthesized...
"It is pretty generally accepted that 6-HO-DMT is inactive. I am not too surprised. There are so few things with open and exposed hydroxyl groups that succeed in making it through the lipid barriers to the brain."
Alexander Shulgin in
TiHKAL (http://www.erowid.org/library/books_online/tihkal/tihkal03.shtml#6-HO-DMT)
(http://www.erowid.org/library/books_online/tihkal/tihkal03.shtml#6-HO-DMT)
Beside that 4-OH-tryptamine is quite sensitive, especially even under slightly basic conditions. You would want to protect the hydroxy first with an apropriate group.