Print Page - Replace Cl with Br on Ketamine phenyl group?

Title: Replace Cl with Br on Ketamine phenyl group?
Post by: Kid on October 31, 2002, 06:56:00 AM

I tried a search but nothing came up. Seemed kind of like an obvious thing to try in order to see if any interesting effects / differences could be found. Anyone ever heard of this being done, to make 2-(2-Bromophenyl)-2-(methylamino)- cyclohexanone?

I suppose any halogen could be used.

Title: You cannot easily modify ketamine like that.
Post by: Rhodium on October 31, 2002, 06:59:00 AM

You cannot easily modify ketamine like that. You must synthesize the bromo-molecule from scratch.

Title: I wasn't interested in synthesis routes
Post by: Kid on October 31, 2002, 07:12:00 AM

Yeah, I realized that you probably couldn't de-chlorinate it and add a bromide ion on there selectively, jeez. I was just wondering if such a compound had been made and if it had been observed to have different effects.

Title: Ask Zealot.
Post by: Antoncho on October 31, 2002, 11:31:00 AM

AFAIK, he has made and tasted the comp'd you're talking about.

Antoncho

The Vespiary

The Hive => Chemistry Discourse => Topic started by: Kid on October 31, 2002, 06:56:00 AM