after reading:
https://www.thevespiary.org/rhodium/Rhodium/chemistry/benzylchloride.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/benzylchloride.html)
https://www.thevespiary.org/rhodium/Rhodium/chemistry/meth.phenylacetaldehyde.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/meth.phenylacetaldehyde.html)
Toluene is refluxed with dried Ca(ClO)2 to yield BenzylChloride by decantation
Benzylchloride is reacted with Magnesium in very dried diethylether and 2-3mg of iodine to yield BenzylMagnesium Chloride
Acetone is reacted with Ethylamine and microwaved-powdered MgSO4 to yield by phase decantation AcetoneEthylimine
AcetoneEthylimine and BenzylMagnesium Chloride are refluxed to yield after hydrolysis Alpha-Methyl-N-Ethyl-amphetamine (methamphetamine like)
Chemistry sounds alright, but N-ethyl-amphetamine is only half as potent as regular amphetamine...
indole_amine
The product wouldn't be N-ethylamphetamine but N-ethylphentermine.
I guess for n-ethyl-amphetamine one would have to use rather acetaldehyde instead of acetone. Correct?
indole_amine
it is quite cross-posting but if acetaldehyde is available, this way is cool too:
Ph-CH2-MgCl + CH3CHO --> Ph-CH2-COH-CH3
Ph-CH2-COH-CH3 + H2SO4(90%)/NaCl --> Ph-CH2-CCl-CH3
Ph-CH2-CCl-CH3 can be extracted very easily (phase separation, toluene should work)
then it is reacted with hexamine (pharmacy store)
The reaction of benzylmagnesiumchloride with acetaldehyde will not yield p2pol in any desirable yields. The product will rearrange to something useless (cant remember what), but there are loads of descriptions in TFSE about this...