The Vespiary

The Hive => Chemistry Discourse => Topic started by: taig on October 14, 2002, 10:07:00 PM

Title: oxycodone -> oxymorphone with hydrobromic acid
Post by: taig on October 14, 2002, 10:07:00 PM

I haven't found that method mentioned on rhodium or elsewhere, but there is a US patent 2806033 that describes how to demethylate oxycodone by boiling with concd hydrobromic acid. I couldn't find the full patent text, does anyone know how that method works and at what yields?

Thanks,

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Title: Patent Text
Post by: carboxyl on October 14, 2002, 10:16:00 PM

http://l2.espacenet.com/espacenet/bnsviewer?CY=gb&LG=en&DB=EPD&PN=US2806033&ID=US+++2806033A1+I+ (http://l2.espacenet.com/espacenet/bnsviewer?CY=gb&LG=en&DB=EPD&PN=US2806033&ID=US+++2806033A1+I+)

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Title: Thanks. Well, it looks like Epikur's mthod at ...
Post by: taig on October 14, 2002, 10:26:00 PM

Thanks. Well, it looks like Epikur's mthod at rhodium has a much better yield.

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_{Slow your speech and lower the pitch of your voice.}