Swibn has been studying the al/hg reductive amination of P2P->meth.
It seems that most reductive amination's concerning MDP2P can be related to that of P2P.
In the following method;
https://www.thevespiary.org/rhodium/Rhodium/chemistry/redamin.os-bs.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/redamin.os-bs.html)
55.2g MDP2P (0.31mol)
66.9g Methylamine.HCl
39.6g 98% NaOH
423mL MeOH
26.1g Al Foil
141mg HgCl2
are used.
If one was to relate this method to P2P, would one use the same molar ratio's, eg:
41.6g P2P(0.31mol)
66.9g Methylamine.HCl
39.6g 98% NaOH
423mL MeOH
26.1g Al Foil
141mg HgCl2
Or would the rest of the precursors have to be scaled differently aswell?
That's exactly how you calculate it.
But if you take a look at my page, there is already a document with the Al/Hg procedure adapted to the synthesis of methamphetamine from P2P (using either 40% MeNH2(aq) or MeNH2.HCl: https://www.thevespiary.org/rhodium/Rhodium/chemistry/p2p-meth.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/p2p-meth.html)