Is ity possible to hydrolize Bromosafrole to MdP2POL With
NaOH Heat and H2O?
VL_
to increase reaction speed, you might either work with
an organic solvent/PTC system or in alcoholic solution.
hydrolysis also works in acidic medium (ie. dil. H2SO4).
you'll always get some elimination side-reaction.
now the $100.000-question is: why would you want to do
that? (halo-safrole => MDP2P?)
It is national bromine month.
thanks for your cooperation :P
That reaction sounds like you are going to get isosafrole as your major product (elimination instead of substitution).
https://www.thevespiary.org/rhodium/Rhodium/chemistry/halide.carbonyl.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/halide.carbonyl.html)
is much better, and if you
really want MDP2Pol, reduce the product from this reaction.