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91
Most phenethylamine, tryptamine, ergoline, etc. drug patents are expired and in the public domain.
92
News / Re: A.I. uses "retrosynthesis" to copy patented drugs without infringing patents
« Last post by gd on February 02, 2019, 02:29:14 AM »
i don't see how an alternate synthesis 'gets around' any such copyright infringement but i know nothing about the law.

i do, however, have a grasp on fair play.

surely it is moreso the product that bears the weight of copyright here, regardless of the route taken ?

mind you and having said that, i'm not sure what would happen if software synthed every possible molecular structure, so the method is definitely intellectual property.

Ok I'm most definitely not particularly knowledgeable when it comes to chemistry (or law, for that matter), but...

It seems to me like particular molecular configurations can't possibly be copyrighted since they're totally naturally occuring (even if synthesized in a lab). I mean, it feels like if someone were to copyright gasoline (goodbye 90% of the fuel industry).

I'm not speaking from a place of certainty or anything, but intuitively it just seems like it can't possibly be.

Even syntheses the though... Like, can someone copyright hydrocarbon combustion????

Some food for thought at the very least, that's for sure
93
News / Re: A.I. uses "retrosynthesis" to copy patented drugs without infringing patents
« Last post by gd on February 02, 2019, 02:15:35 AM »
Chematica was covered here before, awesome software, I which I had excess to it :D

I would love to play around with Chematica myself, if only I had the chance, but, these huge pieces of proprietary software that charge like $10,000 a license (or something like that) aren't always that much more sophisticated than what open source projects can do (with the right amount of dedication and contribution, at least).

It's like Wolfram / Mathematica / etc... Sure, super useful software if you can afford it (or can get a license by some other means), but totally replicable.

The awesome thing about computer science is that the investments are virtually non-existent. I've only recently gotten into chemistry and it's already costing me a small fortune (glassware, precursors, solvents, and the especially fancy shit like Soxhlet extractors, etc).
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News / Re: A.I. uses "retrosynthesis" to copy patented drugs without infringing patents
« Last post by loft on February 01, 2019, 11:47:14 PM »
Chematica was covered here before, awesome software, I which I had excess to it :D
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News / Re: A.I. uses "retrosynthesis" to copy patented drugs without infringing patents
« Last post by chip on February 01, 2019, 10:24:30 PM »
i don't see how an alternate synthesis 'gets around' any such copyright infringement but i know nothing about the law.

i do, however, have a grasp on fair play.

surely it is moreso the product that bears the weight of copyright here, regardless of the route taken ?

mind you and having said that, i'm not sure what would happen if software synthed every possible molecular structure, so the method is definitely intellectual property.
96
News / Re: A.I. uses "retrosynthesis" to copy patented drugs without infringing patents
« Last post by gd on February 01, 2019, 10:57:49 AM »
Quote
The rules are the "basic moves" that are used by graph-search algorithms to navigate enormous trees of synthetic possibilities in intelligent ways.

I just knew I wasn't barking up the wrong tree with my own endeavors (www.thevespiary.org/talk/index.php/topic,16556)...
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News / A.I. uses "retrosynthesis" to copy patented drugs without infringing patents
« Last post by dopamine on February 01, 2019, 05:08:16 AM »
I thought this was pretty interesting, basically this company has developed AI that can reverse engineer drug patents in order to sidestep copyright infringement.  I bet with some tweaking it could also be purposed to sidestep drug laws and create new designer drugs / research chemicals.

Quote
Called Chematica, the software platform does something called “retrosynthesis,” similar to the kind of reverse engineering that takes place when an engineer dissects an existing product to see how it works. In the case of Chematica, this process is based on a deep knowledge of how chemical interactions take place. It has around 70,000 synthetic chemistry “rules” coded into its system, along with thousands of additional auxiliary rules prescribing when particular reactions occur and with which molecules they’re compatible. An algorithm then inspects the massive number of possible reaction sequences in order to find another way to the same finish line.
source: hxxps://www.digitaltrends.com/cool-tech/ai-develop-drug-without-trademark/
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News / Re: South oz bust
« Last post by Helios on January 30, 2019, 02:24:43 AM »
Yuck looks ghetto af, I wonder how pure their products were?
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Harm Reduction Resources / Re: My write up reflecting upon me.
« Last post by warte on January 29, 2019, 05:14:24 AM »
Good on you dude for writing this. I can sense where you are coming from.

Hello from another side,,,, different world.
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Harm Reduction Resources / My write up reflecting upon me.
« Last post by 2modelbs on January 29, 2019, 12:00:18 AM »
It's important to maintain health if you prefer an illegal substance rather than what's legal. For me it started with Coke weed the cheapest beer I can find then on to the back roads 16 years ago . I grew up with out much guidance. Besides my brothers. At that point and time drugs such as cocaine were still some what euphoric, and you could tell you weren't getting high off something else. 14 years ago I tried what people refer to as Ani for the first time. As at least where I'm from it was local and after pondering how cut cocaine really is I didn't buy into the Bull shit of how bad chickenfeed was for you. Mind you it was used infront of me but from.my understanding was probably much more clean that Coke. It was to. but back then I was jus worried about a good buzz for the weekend and goin back to work. It seemed if you know who was making the honey all was well. Then it seemed to change in 2011 to 2013 fast. Coke was way different and crack was the only thing that felt some what like Coke used to, now its gone to. Ice in 2015 was still good. Ice now, all I can tell you and the best way to judge is to try it. If you done the real deal you should be able to tell what's what. Thanks to my brothers being significantly older than me, I was always able to source what I wanted from older more responsible and experienced low key sources. As being a more of somewhat  street person I was always able to depend on the streets(that's a broad term). I heard about DNMs read alot of reviews and it seemed like a bunch of scammers to me as I didn't honestly have to worry about harm reduction until about 2 years ago. When the last of the people I had known had inebitally either went to prison, died, grew up, grew out of it, got their life together or burned a bridge all dependability of having clean shit went out the door. I to have removed myself from the life and just worry about work and a good clean buzz anymore. Rarely that happens. Ice is now really popular, but very few actually really know what good is because of how taboo it was in my area up till a few years ago.

Long story short. Best way to reduce harm reduction imo. Do the real thing. If it feels nothing like it used to and the high is different. Don't buy it. Past ten times I've tried ice it wasn't real. Or contained very little crystal. If I knew if any of the washes actually worked is do a write up. All the people I actually would know that kind of thing wouldn't want to talk about it because the clandestine fun in my area is becoming history and many would like to keep it that way as they've moved on. And the other half would more than likely be more interested in stealing my car to feed their addiction. Which leads to my number two point. Don't let the high be your passion in life. You have to gebout of bed and do something for yourself. I understand life gets hard and changing your mind for a while is what keeps your boots on the morning when the times throw a curve ball at you and you might wonder how your gonna come up with money for bills, and feed the ones who depend on you to keep a roof over their head. But it can't last. You can't let it be the o ly thing that gets u outta bed in the morning. Always at least when thinking becomes critical do so with a sober mindset and evaluate if the people around you are friends or if the only thing in common is drugs.

1. If it don't feel right it ain't.
2. Anymore you would have a better chance making it yourself than finding the real deal it seems
3. Make sure you come back to reality and do so often. You know how people say I don't even know how things got this way. They aren't lying, and I know from experience.
4. Learn to love yourself.
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