Is DMF a tough chemical to acquire?  And wouild it be better just to use Formamide in place of DMF for Bright Star's synthesis.

Yes, dimethylformamide, diethylformamide and formamide are all ok to use as a solvent for ketone production ala Brightstar (says so in the synth, btw). But, easier yet... it's also possible to use MeOH as the solvent.

Just about an polar aprotic solvent should work, though your yeild might suffer. But, if you are going to use alcohol, use Isopropanol.

I was wondering how somone would alter bright star if they wanted to use MeOH as a solvent.

instead of DMF use methanol. Reflux. Look at MethylMan's wacker.

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Author unknown.

its been said on the old board that a solvent like acetone, or dmso could bee used but to my knowledge noone has used it here
r

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i don't worry about the 4 letter words, its the letter words i despise!
DEA,FBI,CIA,NSA,ATF,DOJ

Methanol Wacker:

https://www.thevespiary.org/rhodium/Rhodium/chemistry/wacker.benzo-meoh.html

how did this get boosted? this is ancient.

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-swis54

LOL
formula54, how is the LSD synth coming along?

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Do Your Part To Win The War

very funny. isuppose youve *had* a good night sleep.

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-swis54

For scaling the benzo way up over 1kg dmf is a requirement,
losses are seen with meoh, also less workup!
R

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break the law! Do drugs! Have sex!