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Sensibility of mercapto-groups to reduction

Started by Prometheuz, May 23, 2003, 06:02:00 AM

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Prometheuz

After studying this excellent post

Post 434950

(Chimimanie: "On 2C-T-x precursors", Novel Discourse)
, I wondered if the mercapto-group (or whatever it's called.... My nomenclature-skills are a bit rusty) can stand reduction with LAH?
I recon normal condensation with nitromethane would behave just fine with the compound (Z)?
My knowledge about sulphur-containing compounds is rather limited...


Chimimanie

Hi!  :)  thank you for your comments

Yes the 4-alkylthio groups are stable to LAH, its the way good doctor Shulgin use to synthetise the various 2-CT. (benzaldehyde ->  nitrostyrene --LAH--> amine)

see

http://www.erowid.org/library/books_online/pihkal/pihkal043.shtml



For others question, please use the appropriate thread

Post 434950

(Chimimanie: "On 2C-T-x precursors", Novel Discourse)