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Phenylpropanolamine Source?

Started by xbnmx, February 01, 2004, 08:29:00 PM

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xbnmx

The only viable source of phenylpropanolamine I was aware of was otc pill extraction, but all of these drugs have vanished fromt he shelves and the only ones I am aware of which are still for sale are special pet medications which require a prescription.  Is anyone aware of another source or of a posible synthesis route?

silenziox

What's the wrong with you? Don't you ever take advantage of TFSE, altavista/google or rhodium.ws?

Benzaldehyde+nitroethane+triethylamine to the nitroethene,
then reducting to the alcohol with Zn/formic, for example.


Bandil

Benzaldehyde+nitroethane+triethylamine to the nitroethene
To much THC there eh?  ;)  I think you meant :"to the nitroalcohol"

Follow

this

(https://www.thevespiary.org/rhodium/Rhodium/chemistry/para-fluoro-4-mar.html) procedure and omit the last two steps to get your PPA. Use regular benzaldehyde instead of the fluoroinated version of course!

Regards
Bandil