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How to make scopolamine?

Started by Romik, September 16, 2004, 06:44:00 PM

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Romik

Hi, please tell me how to make scopolamine or give me some links... ;D

java

Try reading this thread......java

Post 407243

(dombo: "Can this be synthesized?", Newbee Forum)



Drug_Phreak

This thread may be helpful to you.

Post 84899 (missing)

(Nocturnal: "D. stramonium/bell***** alkaloids", General Discourse)



claude

If you want some scopolamine, it can be more easy to extract it from Datura or Brugmansia (very common plants) or any other plant from the Solanaceae family. The mix of alkaloids will also contain atropine and hyoscyamine, but I think you can separate them by chromatography.

longimanus

One could possibly convert the quaternary butylscopolamine bromide to the tertiary scopolamine.
 Butylscopolamine bromide (aka Buscolysin) is an OTC spasmolytic and it could be found in any pharmacy (at least in my country).

 BTW, Romik, leave this on the shell after you synthesise it.