Author Topic: A very comprehensive Nef Reaction Review  (Read 850 times)

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Rhodium

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A very comprehensive Nef Reaction Review
« on: April 08, 2004, 06:32:00 PM »
Tetrahedron report number 667
Recent synthetic developments in the nitro to carbonyl conversion (Nef reaction)

Roberto Ballini and Marino Petrini

Tetrahedron 60(5), 1017-1047 (2004)

(https://www.thevespiary.org/rhodium/Rhodium/pdf/nef.reaction.review.2004.pdf)
DOI:

10.1016/j.tet.2003.11.016

 



Abstract
New synthetic approaches and applications of the Nef reaction, appeared in the literature since 1990, are reviewed.


Rhodium

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Transformation of Aromatic Nitroalkanes into...
« Reply #1 on: October 21, 2004, 05:49:00 PM »
Transformation of Aromatic Nitroalkanes into Carbonyl Compounds by the Improved Nef Reaction
H. Chikashita, Y. Morita, and K. Itoh

Synth. Commun. 17(6), 677-683 (1987)

(https://www.thevespiary.org/rhodium/Rhodium/chemistry/nef.two-phase.html)



Abstract
An improved two-layer method of the Nef reaction which is effective for the conversion of a variety of aromatic nitroalkanes into carbonyl compounds is described.
The yields of phenylacetaldehydes from phenyl-2-nitroethanes cluster around 65% while phenylacetone is isolated in almost 90% yield, as are several related benzyl ketones..