Author Topic: Indole-3-MeOH to IAA? Indole-3-prop. acid to ...?  (Read 703 times)

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meme

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Indole-3-MeOH to IAA? Indole-3-prop. acid to ...?
« on: August 27, 2002, 07:49:00 PM »
Does this read OK?

Thanks, everyone, for reading this.  I'm still very dedicated to completing an indole grignard, but am taking some time in college to have at least some reaction experience.

1.)  I posted a little while ago about the condensation of indole and methanol (82%).  Could the tosylate of this be replaced with the CN- ion, and hydrolyzed into IAA?

2.) Indole-3-propionic acid seems to be a very commen dye intermediate . . . A Hunsdiecker bromination-decarboxylation of the silver salt would yield indole-3-Et Br with no massive problems, right?

Much guilt at wasting more bandwidth  . . . forgive me :-[ .  I thank everyone for all I've learned, and for giving me this path to walk.