Author Topic: Aluminum alkoxides for Claisen Condensations?  (Read 765 times)

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wolff_kishner

  • Guest
Aluminum alkoxides for Claisen Condensations?
« on: June 15, 2004, 10:59:00 PM »
I used the search engine to find out if aluminum alkoxides could be used in place of sodium alkoxides in the Claisen Condensation and other enolate reactions, and found out that aluminum isopropoxide couldn't be used because it would undergo a Meerwein-Pondorf-Verley reduction with the resulting ketone. However, wouldn't a primary aluminum alkoxide, such as aluminum ethoxide or methoxide work for Claisen condensations? To my knowledge, primary alkoxides do not cause Meerwein reductions.

psyloxy

  • Guest
why ?
« Reply #1 on: June 20, 2004, 05:02:00 AM »
I don't know, but think learning how to prepare NaOEt etc would be easier than finding out.

Post 257912

(Antoncho: "Alkali metal alkoxides: finally, OTC!", Novel Discourse)

Post 512239 (missing)

(psyloxy: "some great alkali alkoxide patents", Chemistry Discourse)

Post 460620

(psyloxy: "magnesium methoxide - Mg alkoxides - Mg, I2, ROH", Chemistry Discourse)
... don't know about using Mg(OMe)2 in a claisen condensation, though.

--psyloxy--