Author Topic: Scaling "p-benzo from hydroquinone/H2O2"  (Read 682 times)

0 Members and 1 Guest are viewing this topic.

abuse

  • Guest
Scaling "p-benzo from hydroquinone/H2O2"
« on: September 28, 2003, 02:59:00 AM »
The synth for p-benzo from hydroquinone/H202 listed at Rhodiums page is set up for yielding 50g p-benzo from 55g of hydroquinone. I'm curious to know if anyone actually tried this synth at a larger scale, say, 100-150g of hydroquinone. Would it be simple enough to double all quantities if one were to scale the reaction at 2X?

hest

  • Guest
Scaling
« Reply #1 on: September 28, 2003, 12:46:00 PM »
Yes.
Usual you don't need to scale the solvent with 100%.

abuse

  • Guest
The synthesis says that a 4-neck flask fitted...
« Reply #2 on: October 29, 2003, 02:42:00 AM »
The synthesis says that a 4-neck flask fitted with an addition funnel and thermometer are required. Does the thermometer need to be submerged inside the reaction contents, or does is just need to be suspended inside the flask?

blaaky

  • Guest
temperature...
« Reply #3 on: October 29, 2003, 06:50:00 AM »
I use a 3 neck flask and yeah submerge the bulb of the thermometer to get a good reading...

blaaky


abuse

  • Guest
Hypothetically speaking, is the synthesis...
« Reply #4 on: October 30, 2003, 01:27:00 AM »
Hypothetically speaking, is the synthesis difficult? How important is tempurature monitoring? Are there any comments or suggestions that you might recommend on the synthesis?