Author Topic: Solid Phase Research  (Read 1756 times)

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Alkylight

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Solid Phase Research
« on: August 15, 2001, 04:31:00 PM »
Does anyone know if there is any scope for the developement of new drugs using solid phase chemistry.  I was thinking of anchoring the basic amphetamine subunit to the solid phase using a linker known as the 'bromo WANG' linker.  Basically just a resin bound benzylbromide.  I have a bit of experience with solid phase organic chemistry.  I have been playing with this idea for a little while now and I was wondering if it has any worth.  Could a whole new library of say amphetamine type drugs be built up this way??

foxy2

  • Guest
Re: Solid Phase Research
« Reply #1 on: August 17, 2001, 07:13:00 PM »
General Combinatorial Synthesis of Tertiary Amines on Solid Support.
Tetrahedron letters
42 (2001) 133-136

This is more applicable to some tryptamine goodies.



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