Author Topic: Grignard side products  (Read 595 times)

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alchemy_bee

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Grignard side products
« on: April 25, 2002, 07:46:00 AM »
After Hydrolysis of the grignard reagent eg with dilute HCl What are the side products? Im currious to understand what happends to the NMgCl complex.



Can a bee be visa vis its entity when half a bee philosophically must ipso facto half not be?

Rhodium

  • Guest
Mechanism
« Reply #1 on: April 25, 2002, 10:26:00 AM »
The =NMgCl complex reacts with HCl to give MgCl2 and the imine =NH, and the imine is then hydrolyzed by H2O/HCl to give the ketone =O and NH4Cl.

alchemy_bee

  • Guest
grignard reactions
« Reply #2 on: April 25, 2002, 05:23:00 PM »
Whow thats great Rhodium, its easy to see how water is detramental to NaBH3 reductions of P2Ps.

Can you explain the attraction/reaction of the nitrogen in the methyl cyanide to the grignard set (MgCl)?


To any bees interested in grignard reactions

http://www.chem.ucalgary.ca/courses/351/Carey/Ch14/ch14-3-1.html

is a good read.





Can a bee be visa vis its entity when half a bee philosophically must ipso facto half not be?

Rhodium

  • Guest
RMgX + RCN
« Reply #3 on: April 26, 2002, 04:12:00 AM »
One of the resonance forms of a nitrile is R-C+=N- and the grignard reagent is equivalent to a R- anion, therefore it adds to the nitrile carbon.