Author Topic: Piperonal from 3-4OH Bzaldehyde?  (Read 1325 times)

0 Members and 1 Guest are viewing this topic.

SweetChem

  • Guest
Piperonal from 3-4OH Bzaldehyde?
« on: October 30, 2001, 04:13:00 PM »
I don't find any process to synthetize piperonal from 3-4 dihydroxybenzaldehyde. Is it possible to do like the first step of this synth with benzaldehyde insteed benzene?

[url=https://www.thevespiary.org/rhodium/Rhodium/chemistry/safrole.html





... crazy synth for sweet dreams ...

Rhodium

  • Guest
Re: Piperonal from 3-4OH Bzaldehyde?
« Reply #1 on: October 30, 2001, 04:37:00 PM »
3,4-dihydroxybenzaldehyde is also known as protocatechualdehyde.
Methylenation reactions can be found in

https://www.thevespiary.org/rhodium/Rhodium/chemistry/methylenation.html#methylenation


foxy2

  • Guest
Re: Piperonal from 3-4OH Bzaldehyde?
« Reply #2 on: October 30, 2001, 07:02:00 PM »

Post 225611

(foxy2: "Re: 4-Methylaminorex Synth w/o CNBr", Novel Discourse)


Post 225616

(foxy2: "Re: 4-Methylaminorex Synth w/o CNBr", Novel Discourse)


Keep reading.

Do Your Part To Win The War

SweetChem

  • Guest
Re: Piperonal from 3-4OH Bzaldehyde?
« Reply #3 on: October 31, 2001, 02:26:00 PM »
Thanks !
But now the problem is that I don't own an autoclave. Is it possible to replace CH2Cl2 by CH2BR2(b.p. 97°)and reflux the whole instead heat under presure?

... crazy synth for sweet dreams ...

Rhodium

  • Guest
Re: Piperonal from 3-4OH Bzaldehyde?
« Reply #4 on: October 31, 2001, 04:59:00 PM »
Yes, dibromomethane or diiodomethane may be used instead. In the link I posted there are a PTC reaction which does not use an autoclave too.