Author Topic: very OTC Amph et MethAmph synths  (Read 4333 times)

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acx01b

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very OTC Amph et MethAmph synths
« on: October 25, 2004, 06:48:00 PM »
after reading:

https://www.thevespiary.org/rhodium/Rhodium/chemistry/benzylchloride.html


https://www.thevespiary.org/rhodium/Rhodium/chemistry/meth.phenylacetaldehyde.html



Toluene is refluxed with dried Ca(ClO)2 to yield BenzylChloride by decantation

Benzylchloride is reacted with Magnesium in very dried diethylether and 2-3mg of iodine to yield BenzylMagnesium Chloride

Acetone is reacted with Ethylamine and microwaved-powdered MgSO4 to yield by phase decantation AcetoneEthylimine

AcetoneEthylimine and BenzylMagnesium Chloride are refluxed to yield after hydrolysis Alpha-Methyl-N-Ethyl-amphetamine (methamphetamine like)

indole_amine

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Ethamphetamine
« Reply #1 on: October 25, 2004, 07:11:00 PM »
Chemistry sounds alright, but N-ethyl-amphetamine is only half as potent as regular amphetamine...


indole_amine

moo

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The product wouldn't be N-ethylamphetamine but
« Reply #2 on: October 25, 2004, 07:35:00 PM »
The product wouldn't be N-ethylamphetamine but N-ethylphentermine.


indole_amine

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reason?
« Reply #3 on: October 25, 2004, 07:48:00 PM »
I guess for n-ethyl-amphetamine one would have to use rather acetaldehyde instead of acetone. Correct?


indole_amine

acx01b

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it is quite cross-posting but if acetaldehyde...
« Reply #4 on: October 25, 2004, 08:41:00 PM »
it is quite cross-posting but if acetaldehyde is available, this way is cool too:
Ph-CH2-MgCl + CH3CHO --> Ph-CH2-COH-CH3
Ph-CH2-COH-CH3 + H2SO4(90%)/NaCl --> Ph-CH2-CCl-CH3
Ph-CH2-CCl-CH3 can be extracted very easily (phase separation, toluene should work)
then it is reacted with hexamine (pharmacy store)

Bandil

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The reaction of benzylmagnesiumchloride with...
« Reply #5 on: October 25, 2004, 09:37:00 PM »
The reaction of benzylmagnesiumchloride with acetaldehyde will not yield p2pol in any desirable yields. The product will rearrange to something useless (cant remember what), but there are loads of descriptions in TFSE about this...


Offline sophie7

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Re: very OTC Amph et MethAmph synths
« Reply #6 on: March 24, 2016, 02:45:40 PM »
Prefer  benzyl  to a-phenylacetonitrile and finaly BMK.
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Offline Tsathoggua

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Re: very OTC Amph et MethAmph synths
« Reply #7 on: June 25, 2016, 08:37:55 PM »
Bandil, doesn't the order of addition make a difference?  Could have sword reading something to that effect.
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