Author Topic: Hexamine for Knoevenagal  (Read 930 times)

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IudexK2

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Hexamine for Knoevenagal
« on: October 25, 2001, 07:10:00 PM »
Would hexamine work as a catalyst in the Knoevenagal condensation?

Many thankx,
IudexK

Rhodium

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Re: Hexamine for Knoevenagal
« Reply #1 on: October 25, 2001, 07:16:00 PM »
Probably not, as the nitroalkane would probably react with the formaldehyde parts of the molecule if the hexamine would hydrolyze. It is also only very weakly basic in its unhydrolyzed form.