Author Topic: 1,4-Butanediol via grignard of 1,2-dibromoethane  (Read 1011 times)

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a3d0a3m

  • Guest
1,4-Butanediol via grignard of 1,2-dibromoethane
« on: February 11, 2004, 12:51:00 PM »
SWIM was thinking that 1,4-butanediol could be formed by a grignard reaction with formaldehyde and 1,2-dibromoethane... would this conceivably work?

a3d0a3m

Rhodium

  • Guest
1,2-dibromoethane grignard
« Reply #1 on: February 11, 2004, 02:27:00 PM »
No, as you cannot form a grignard reagent of 1,2-dibromoethane.

Br-CH2-CH2-Br + Mg -> H2C=CH2 + MgBr2


hypo

  • Guest
cost-benefit analysis???
« Reply #2 on: February 11, 2004, 02:49:00 PM »
if you're ready to such lengths to make a simple
aliphatic alcohol, why not reduce succinic (or fumaric
or maleic) acid? just buy a bottle of vodka.