oerlikon is on the money about antiemetics and opiates i took 10 grams of kratom and only 50 mg of dimenhydrinate.
and it feels much nicer than kratom alone.
a popular thing was codiene and promethiazine or phenergan.
a weak opiate like codiene is potentiated substantially by an antiemetic so the principal is a very sound idea.

i've mixed heroin and tramadol so i'm pretty sure codeine is safe.
the two boost each other nicely

I read about that problem,but biggest dose of codeine I ever taken was cca. 200mg and
effect were very very light,maybe this combo will answer is it really P450-2D6 deficiency
or just too low dosage on such a big guy.

I tried codeine+tramadol since some people reported great synergy,but I got  with mixed results,
probably due too much caffeine in extract.Now I washed water extract with toluene before evaporating,
so this should remove most of it.

And yes,Dramina is diphehnydramine,but since we allready discused that in previous posts
it is more convenient and less prone to typing errors to call it Dramina.
I heard that this stuff is actually illegal in some African countries.

Seems that codeine+tramadol+dramina is BAD combo.
Very good against pain,makes you totaly numb,but you actually feel very anxious and hostile.
I never had mood swings so intense nad rapid,from euphoria to panic and disphoria in seconds!
Since I was in extreme state of depression before taking it,I was affraid I gone totaly crazy,
much like bad trip! Only after codeine exited system I feel good from tramadol alone.

Oh well! at leasted I learned something!
You can't find good combo every time!


Jon,what do you mean!?
If St. John's Wort helps me that means I have or haven't  P450-2D6 deficiency !?

Interesting,since st. john's wort and tramadol are labeled as combo to avoid,since it can cause serotonin storm.
This "serotonin storm" thing confuses me!
I get allmost all the symptoms from use of drugs like MDMA or Tramadol,so am I realy having
serotonin storm then!? I mean,can effects of these drugs be described as serotonin storm!?

While many of the effects listed sound simular to Seretonin syndrome trust me when I say that Seretonin syndrome is indeed no pleasure. Extreme fever, mild to extreme convulsions and an over all feeling of terror. While MDA can cause SS when combined with SSRI's the flood itself is caused by a different mechanism then when MDA is used alone.

MDA may flood the brain with Serotonin but it is able to still break down. Its when you have a combination of this with something that does not allow it to break down such as an MAOI that it becomes a serious issue. Of course large doses of Serotonin re-leasers such as MDA or sensitivity to such substances can cause the same issue such as in my case of SSRI use but the general population shouldn't be to concerned unless they notice the symptoms. As far as I know its generally pretty rare but I could be wrong.

Keep in mind about side effects is that when a drug company perscribes a substance like an opiate the effect desired is pain relief. Euphoria is an unfortunate side effect of this and I do indeed mean that. If it wasn't for this side effect larger doses could be taken without ill effect. Better to design a drug for Euphoria then have it as a side effect because then you will more then likely acquire restrictions for this substance causing it to lose its value to many people who could have otherwise benefited from it.

sedit you are correct it is well known that 14 substitution of morphine like opiates result in euphoria so they come out with time released versions and so on but really they know what they are doing they just do this kind of shit to cover thier asses you think perdue pharma gives a shit?