Author Topic: Most efficient method for cannabis extraction,need help...  (Read 375 times)

Oerlikon

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Most efficient method for cannabis extraction,need help...
« on: December 29, 2010, 03:33:00 AM »
I know that this subject might have been discussed numerous times
but it is really urgent... :-[
I am interested which is best method of extracting most of the canabinoids from cannabis?!
I have DCM,chloroform,IPA,MeOH,EtOH,acetone and toluene available as solvents.
Butane is ha(za)rd to work with and I lack proper apparatus,DCM and acetone seems to be prime candidate.

Since some of you might know that THC is not only important ingredient in cannabis,it is desirable
to chose solvent that will extract all of these but not to extract wax nad other crap.
I know it can be and has been done sucesefully by using some of these solvents many times
but I started this tread so you can share your best experince,methods...
Cannabis is rather expensive here now,illegal and has low % of active ingredients.

Elderly relative with diabetes,removed pancreas and multiple liver problems (including cancer)
came to phase when extreme nausea and almost total lack of appetite became serious problem.
Patient is refusing most of conventional treatments due the extreme phobia of
hospitals and severe depression.
I know that some weed might help significantly for nausea and appetite,
if nothing else than for improving life quality.
Patient is more than 80yr old,newer smoked,previously good health
and won't even consider taking cannabis voluntarily,so adding few drops of
cannabis extract in tea or milk is desireable method.

Thanks in advance!
« Last Edit: December 29, 2010, 03:43:21 AM by Oerlikon »
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jon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #1 on: December 29, 2010, 04:33:58 AM »
acetone soxhlet extraction works nicely or if you have hexane on hand you have to soxhlet extract it.
then react it with propionic anhydride add methanol stir over night and evap off the methylpropionate at around 80C or so.

Sedit

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Re: Most efficient method for cannabis extraction,need help...
« Reply #2 on: December 29, 2010, 04:56:34 AM »
Will that person consider the use of various JWH or WIN compounds? Some of these in studies have been showed to induce tumor regression, blood sugar modulation, pain relief and appetite stimulation.

Still out of all the solvents you listed I would go with the most polar yet volitile of all being either DCM or Chloroform. You will get alot of other things comming along for the ride using and alcohol or acetone as the solvent. Butane extraction is fast and simple to accomplish so personally I would use that but if you fear it then use DCM instead.
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akcom

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Re: Most efficient method for cannabis extraction,need help...
« Reply #3 on: December 29, 2010, 05:05:56 AM »
Coleman camping fuel (mostly hexane) works very well.

jon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #4 on: December 29, 2010, 05:07:47 AM »
acetone does a nice not perfect job of cleanly extracting cannabis.
you can then esterify it in whatever solvent you extracted it into and remove the acid anhydride by stirring with methanol to make the methyl ester which is much more volitile and evaporates easily.

hypnos

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Re: Most efficient method for cannabis extraction,need help...
« Reply #5 on: December 29, 2010, 07:19:38 AM »
oerlikonmon  etoh  has been found to be highly effective for these purposes

  It will nicely extract ALL those oily compounds, using this SIMPLE method

step 1)  get at least 1litre per 50gms (maximum for complete extraction) and get a two litre ptfe bottle

 step 2) grind up desired material as finely as possible IMMEDIATELY BEFORE placing it into the ethanol

 step3) shake the shit out of it for as long as one can be bothered, then place in a dark place <20c and    shake it as often as you can remember to for the next 12-24hrs until you cannot see through it-(hold it up to the sun!!!)-it should be a deep dark green/brown almost opaque liquid 8)

 step 4) strain several times using first something like  cheesecloth and then through something finer, like a t-shirt--(DONT FORGET to pre-moisten your filters with etoh) and then do the final filtering with fine grade coffee filter papers--vacuum helps lots ;)

step 5) now there will be a lovely deep red solution of around 8-900 mls which needs the solvent removed..any way you like...BUT...if so desired when about 100ml is left add 20 drops of conc. Hcl and mix well....leave for a couple of hours at room temp, and then evap the rest of the solvent and.....
   VOILA..there will be a lovely deep red VERY viscous oil...enjoy ;D

 hyppy
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jon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #6 on: December 29, 2010, 07:38:01 AM »
were talking about pure processes ethanol drags tars and oils with it.
acetone is nice i'[ve tried it myself and when you add propionic anhydride the thc molecule just sings when it hits your brain.

hypnos

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Re: Most efficient method for cannabis extraction,need help...
« Reply #7 on: December 29, 2010, 07:57:49 AM »
we're talkin "effective extraction" not pure processes....acetone WONT 'drag tars and OILS with it'???

this extraction process is well proven and the isomerization has a variety of possibities and doesnt use PA-which aint exactly OTC.....but interesting nonetheless...What do you think is happening when you 'propionate' your 'oils'?

We've do have a LOT of CBN receptors though................
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jon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #8 on: December 29, 2010, 08:19:47 AM »
well the propionyl ester is mighty fine better than the acetyl ester it is pure euphoria zero anxiety best i could describe it .
the euphoria was a bit embarassing like meglomania beyond normal euphoria perhaps not good.
acetone will drag some tars but not many i've done it esterified it in acetone and was fucking pleased to the hilt how can i say more?
one hit and quit on all my test subjects after one hit they had to hit the fast food restaraunts they forgot about the dope what more do you want?
« Last Edit: December 29, 2010, 08:43:45 AM by jon »

hypnos

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Re: Most efficient method for cannabis extraction,need help...
« Reply #9 on: December 29, 2010, 11:05:11 AM »
  thanx for your feedback,,but what I would REALLY like to know,is, "what do you think occurs to the 'cannabinols/oids' when the are 'propionated?' ???
   
Quote
how can i say more?
one hit and quit on all my test subjects after one hit they had to hit the fast food restaraunts they forgot about the dope what more do you want?
  Well not fast fuckin SHIT that goes under the misnomer of "food"....yeah sure its contains kilojoules a plenty,, BUT it aint got those NECCESSARY life promoting substances,,that I consider an ESSENTIAL part of my diet

   As soon as I have some more time, I will go into this topic (re; food and what we NEED from it) in MUCH greater detail, with enough references to numb your mind,, :o

  I'll pm you soon jonmon as I have some stuff I need your advice/POV about,,,plus I'll send you an 'e addy' some you can send me some data more easily

  I hope you're feeling better and your mum aint doing your head in too badly :P

  Cheers for the New Year amigo....Hyppy :'(
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jon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #10 on: December 29, 2010, 01:43:18 PM »
mum is always a bipolar bitch like i am she's more afraid of me though i tend to be violent.
you know society puts that violent sticker on you and where can you work? ahh but i found me niche,undertaker i can con grieving familes out of thier savings with a smile on my face and, i'm not dealing with "people" just carcasses.
they don't give me any bother and i'm not scared of death.
it suits me fine. i could care less
on to your question it makes it more lipophilic, if you know anything about drug chemistry lipophilicity means it crosses the blood brain barrier more effieciently.
« Last Edit: December 29, 2010, 01:53:25 PM by jon »

Oerlikon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #11 on: December 29, 2010, 07:07:24 PM »
Thank you all on responses!
DCM and acetone are two prime candidates for me.

No Sedit,person is too old and will not voluntarily take anythin he considers to be "a drug".
Slipping some in tea or milk is only option,at least until realization that this is not something
terrible but healthy.
Can I make tea out of "Spice" and other JHW containing herbal blends?!

Jon has great idea here,if I understood correctly he is making weed equivalent of heroin.
I had same idea some time ago to do this with morphine to make supeheroin,
propionate equivalent of diacetylmorphine!
Prolonging the carbon chain makes substance more lipophilic!

Unfortunately I don't have chemicals to try this idea nor weed "extraction"(actually reaction) that
way,but it's still a great idea!
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rnr

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Re: Most efficient method for cannabis extraction,need help...
« Reply #12 on: December 30, 2010, 07:39:03 AM »
swim has 2 pdf's that may be very useful viv-a-vis your inquiry.

1.Cannabis Alchemy by D.Gold
2.Marijuana Chemistry, Genetics, Processing, & Potency by Michael Starks (2nd ed)

should be readily available online if swiyou looks hard enough, many solvents and extraction methods are discussed...
Grasscity may be a good forum to search in as well, though terribly unscientific

edit: found attach option  ::)
« Last Edit: December 30, 2010, 08:44:34 AM by rnr »

letters

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Re: Most efficient method for cannabis extraction,need help...
« Reply #13 on: January 01, 2011, 07:38:33 PM »
the method known as QWISO (Quick Wash with Isoproanol) works well in lieu of alkanes/pet. ether
2-5minutes wash with the 90% isopropanol usually yields a brown to golden residue which is very active and potent.
However, for best results, you really should use alkanes like jon suggested. Hexane, Pentane, Cyclohexane, Petroleum ether (40-60, 60-80) are all very good.
When done right, washing with water after extraction and drying of the alkane phase, followed by evaporation and high vacuum usually yields a golden honey colored product, which evaporates fully without a residue on heating.
The alkanes will give you the purest resin possible without distillation or chromatographing methods. Butane, being an alkane, yields a comparable product.

Oerlikon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #14 on: January 06, 2011, 05:05:39 PM »
Will stick with pentane,hexane,DCM and chloroform and inform you how it went...
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Methansaeuretierchen

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Re: Most efficient method for cannabis extraction,need help...
« Reply #15 on: February 15, 2011, 04:16:08 PM »
Soxhlet and low boiling petrolether ist the way of choice - does extract nearly 100% of all cannabinoids from the plant source.

If you want "pure" stuff high vacumm destillation of this extract (dry with MgSO4 etc. before destillation!) should lead to your target.

Btw: You can get very clean low boiling Petrolether in any pharmacy, it's used to remove sticky plaster residues from skin. It's mostly pure pentane and some hexane.

Forget DCM, TCM and Acetone.

lugh

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Re: Most efficient method for cannabis extraction,need help...
« Reply #16 on: February 15, 2011, 05:58:47 PM »
The optimal arrangement of glassware for the extraction of cannaboids involves the use of a percolator  ;)  Since the cannaboids are terpenes, hydrocarbon solvents are preferable as opposed to ketones, alcohols or chlorinated hydrocarbons  8)
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Oerlikon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #17 on: February 15, 2011, 07:18:30 PM »
Low b.p. petrol ether sounds good.

Since I will use only small amounts new glassware is out of question.
Flask and Lebig condenser as reflux will do the trick.
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lugh

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Re: Most efficient method for cannabis extraction,need help...
« Reply #18 on: February 15, 2011, 08:01:47 PM »
As was posted in:

https://the-collective.ws/forum/index.php?topic=21193.0

a hole can be drilled in the  bottom of a glass bottle to create a small percolator  ;)  It's also possible to create a usable percolator from sheet metal, perhaps an old Hive post concerning that can bee located   8)
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Oerlikon

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Re: Most efficient method for cannabis extraction,need help...
« Reply #19 on: February 17, 2011, 08:02:07 PM »
I don't see why coffee percolator can't be used! ;)
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