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Author Topic: Re: deschloro loperamide  (Read 34 times)

fresh1

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Re: deschloro loperamide
« on: November 13, 2011, 04:45:30 AM »
Thanx jon that helps


"You kids need to keep the chemistry to one thread and the pharmacology to the other"

 I see your point enkidu, but how could "we" reasonably discuss this type of problem? Do you think this should be in the Pharmacology thread?

In many ways imo this does fall under "extraction and synthesis"  It would help if you might be able to clarify this issue for further topics/posts as it does kinda fall into a subset of both topics

Cheers f1
« Last Edit: November 13, 2011, 04:47:08 AM by fresh1 »
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RoidRage

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Re: Re: deschloro loperamide
« Reply #1 on: November 13, 2011, 04:47:58 AM »
Hey fresh1, it's not complicated, is it pharmacology or chemistry??! As far as I know, Enkidu is being clear here..

fresh1

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Re: Re: deschloro loperamide
« Reply #2 on: November 13, 2011, 05:04:51 AM »
well considering pharmacology is technically a profession which uses chemistry to "uncover/make" compounds which are biologically active,, I am  a bit confused :o(whats new?)
Quote
As far as I know, Enkidu is being clear here..

   maybe I'm being a bit pedantic,, but as I said, it couldn't hurt to "clarify" this,, RoidRage would you like to rty and define the difference?
 
Matey I'm not having a go at you, I just think some clarification would help everyone (including myself!) to post topics in the most appropriate place...

Thanx for caring though

 f1
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Vesp

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Re: Re: deschloro loperamide
« Reply #3 on: November 13, 2011, 05:27:42 AM »
Considering the fact that this is called "Drug Synthesis & Extraction" and not chemistry, it doesn't matter if pharmacology uses chemistry or not, it still does not belong here.
Only drug synthesis and extraction belong here.
Pharmacology is the branch of medicine and biology concerned with the study of drug action... Not their synthesis or extraction. It is pretty clear if you know the definitions of the words and also read the descriptions of the sections.

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Drug Synthesis & Extraction
Discuss methods for extracting and synthesizing drugs.

Other Chemistry
Discuss chemistry that doesn't fall into the Drug Synthesis & Extraction section.

Pharmacology
Discuss the action drugs have on the body, such as metabolism, receptor activation, bioavailability, etc.

What I believe Enkidu is trying to say is that we need to halt the bastardization of threads by mixing two discussions into one. Clearly we are talking about both the chemistry and the pharmacology of loperamide derivatives in this thread. It would be better to have a pharmacology thread about loperamide derivatives that does not concern itself with their synthesis, and than a synthesis of loperamide derivatives thread that does not concern itself with toxicity.

Having two discussions (chemistry vs pharmacology) competing with each other make it difficult to extract the information you are seeking from the thread and encourages it to be further derailed.

Feel free to start or continue the discussion of the pharmacological properties of loperamide derivatives in the appropriate threads..

This looks like a good one to discuss pharmacology in... Phamacologic characteristics of a loperamide derivative
« Last Edit: November 13, 2011, 05:32:34 AM by Vesp »
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fresh1

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Re: Re: deschloro loperamide
« Reply #4 on: November 13, 2011, 03:00:20 PM »
thanx for the reply vesp that kinda makes sense :)...although sometimes its hard to separate the two,,particularly here,, as jon is suggesting a synthesis,which starts with the "extraction" of the lope,and then changing it to something else,, and to justify doing so,,the pharmacological behavior of the product ,, is, the motivation for doing so....as is the case for most compounds mentioned here,,is it not?

Dont you think it would be "better" to merge threads, rather than have very similar topics posted all over the forum?
 
And btw, sasha includes bioassays, and all sorts of pharmacological opinions, with many of the things he synthesized,,so how does one classify books like P/TIHKAL??? as they contain both,,and are 'referred to' here a bit!

honest, I'm not just "trying to be difficult" in fact quite the opposite!

cheers f1 :P
« Last Edit: November 13, 2011, 03:04:33 PM by fresh1 »
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