Author Topic: mda freebase  (Read 477 times)

German

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Re: mda freebase
« Reply #20 on: October 04, 2009, 05:37:36 AM »
Glad to hear German!  ;D  swim hates when inexplicable problems keep reoccurring with very valuable goods

Oh the tar is good, real good, but it is still tar. I'd rather deal with oil or salt cuz tar is kind of a mess.
« Last Edit: October 04, 2009, 05:44:45 AM by German »

poisoninthestain

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Re: mda freebase
« Reply #21 on: October 04, 2009, 04:50:00 PM »
German, I've read Rhodium once before say that MDA freebase forms the carbonate salt rather quickly.  it ends up as something more like gummy crap rather than oil, that's the carbonate.  however the carbonate salt can go right back to the freebase if something drives off the co2, ie: heat, etc.  i haven't heard much about the carbonate salt other than of course it's active and not as stable as the hcl salt.

MDA freebase does not form the carbonate upon standing in ambient air. See entry #100 in PIHKAL.

jon

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Re: mda freebase
« Reply #22 on: October 06, 2009, 02:41:41 AM »
sounds like some gooped up mda to me try washing it a few times w/ water.
particularly the bromosafrole rxn you see tars and around 50% mda not bad all in all the tars have different solubilities in water dependng on if it's acid or base tends to crash out of bases swij won't be doing any x chemistry for a minute until he's sure he's not under scrutiny.

German

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Re: mda freebase
« Reply #23 on: October 10, 2009, 04:56:43 AM »
Has anyone smoked MDMA?

Should throw some freebase in an oil pipe Jon! Give us a bioassay of that!

" The free bases are volatile and, indeed, amphetamine itself was first marketed in this form in an inhaler, for use as a nasal decongestant. Theoretically, MDMA and MDEA could also be used in this fashion, but the methylenedioxy group raises the boiling point of the free base so high that it is impossible to use it by sniffing the vapour."

From:

http://www.cmaj.ca/cgi/content/full/165/7/917


EDIT: Although then again I guess you meant from some very pure crystals.

German

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Re: mda freebase
« Reply #24 on: October 10, 2009, 05:02:42 AM »
Something very interesting (and important to MD users) also found at that posted site:

"The drug is broken down metabolically, mainly in the liver, where an enzyme designated CYP2D6 is chiefly responsible. However, several different enzymes are involved in its degradation, and some of these appear to be saturated at relatively low concentrations of the drug. Consequently, as the dose is increased and the higher-affinity enzymes are saturated, disproportionately large increases in blood and brain concentrations of the drug occur. Therefore, small increases in dosage may carry the risk of large increases in toxicity."

Also interesting:

"Elimination of the drug from the body is moderately slow, the half-life for MDMA disappearance from the blood being of the order of 8 hours. Because it takes about 5 half-lives (i.e., about 40 hours for MDMA) for over 95% of the drug to be cleared from the body, this may explain the persistence of troublesome after-effects for one or 2 days after use. Some of the metabolites of MDMA are still pharmacologically active, especially its first metabolite, MDA, so that the duration of action may be somewhat longer than the duration of MDMA itself in the body."

And:

"The MDMA isomers also differ in the rate at which they are converted to their corresponding MDA metabolites. It is, therefore, possible that some of the striking interindividual differences in the intensity, time course and toxicity of the effects of ecstasy may be related to individual differences in the metabolic handling of the isomers. "
« Last Edit: October 10, 2009, 05:13:50 AM by German »

German

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Re: mda freebase
« Reply #25 on: October 11, 2009, 01:52:35 AM »
Does anyone else like less MDA rather then more? It seems like 100 to 140 gives a really nice mellow euphoric happy roll but between 150 to 200 the speed really ends up driving the experience.

jon

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Re: mda freebase
« Reply #26 on: October 11, 2009, 05:02:15 AM »
well keep going after the speedy effects wane and it does'nt matter how much you take it gets mellow again.
mda is really hard to od on swij has prooven this many times.

German

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Re: mda freebase
« Reply #27 on: October 11, 2009, 05:26:55 AM »
Yeah I know I tried to look for a fatal dose and I couldn't find one. The closet I could find was one guy who took 7,000mg and a bunch of barbiturates and other drugs. Every other fatality was either a rare allergic reaction or from doing something stupid on the drug like jumping off a balcony (which isn't the drug's fault).

German

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Re: mda freebase
« Reply #28 on: October 12, 2009, 08:07:32 AM »
Touching on what I was referring to above about slight increases in dose having an exponential affect:

"Data from clinical MDMA studies show that there is a complex relationship between MDMA dose and blood levels of the drug and its metabolites (de la Torre, 2000; Mas, 1999). It appears that MDMA inactivates one of the enzymes in the liver that is important to its metabolism (an enzyme known as cytochrome p450 isozyme 2D6 or 'CYP 2D6') (Brady, 1986; Wu, 1997). As a result, small increases in dose can lead to large increases in drug exposure. When dose was increased from 120 mg to 150 mg, drug exposure almost doubled in human volunteers, as measured by area under the curve of MDMA plasma concentration verses time (de la Torre, 2000). However, formation of some metabolites remained approximately constant. These complex dose-dependent pharmacokinetics in humans further increase the difficulty of estimating dose conversions between species. Nonetheless, these human studies with MDMA do suggest that doses above 120 mg may be associated with unexpectedly increased drug exposure and therefore risks of toxicity."

jon

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Re: mda freebase
« Reply #29 on: October 12, 2009, 12:43:55 PM »
well swij played the crash dummy and and smoked some mda he dipped it in  a cigarrette and smoked away it ws like and instant ecstacy trip.
eye wigging commenced immediately.
it was horrible onthe throat althoghit did have that sweet candyshop taste.

German

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Re: mda freebase
« Reply #30 on: October 12, 2009, 07:00:39 PM »
Dude with your dosages and frequency you should really watch it. You are most likely doing some major permanent damage to your serotonin receptors. You're really not suppose to take it more then once a month. After reading an article summarizing all currently available research for 2 hours last night over at Erowid I don't think I'll take more then 100mg more then once a month.

NeilPatrickHarris

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Re: mda freebase
« Reply #31 on: October 13, 2009, 12:12:38 AM »
Yeah I know I tried to look for a fatal dose and I couldn't find one. The closet I could find was one guy who took 7,000mg and a bunch of barbiturates and other drugs. Every other fatality was either a rare allergic reaction or from doing something stupid on the drug like jumping off a balcony (which isn't the drug's fault).

aside from the 500mg IV death during US Army trials while looking for a truth serum, i haven't heard of any other shockingly low fatalities.

German

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Re: mda freebase
« Reply #32 on: October 13, 2009, 12:19:26 AM »
Yeah I've heard to stay away from IV and smoke. Ever IV and smoke experience I've read about was very negative because it was way too intense. It's like condensing an 8 hour experience down into 10 or 15 minutes. It's like getting hit with all 8 hours all at once. And that's exactly what is happening too because when you eat it it's half-life is 8 hours. It takes a while to metabolize. Some will still be in your system 48 hours later (hence way you can be awake for 2 days). But when you inhale or IV it just straight hits you. All two days worth all at once. Just too much.

jon

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Re: mda freebase
« Reply #33 on: October 14, 2009, 04:25:15 AM »
serotonin smearatonin ahh fuck it
i ate truckloads i'm pefectly fine.
in reality all it does is deplete it and it takes 2 weeks to regain the stores that's it.

Sedit

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Re: mda freebase
« Reply #34 on: October 14, 2009, 04:44:22 AM »
Quote
i ate truckloads i'm pefectly fine.

LMAO Well this could all be a matter of opinion so best to not play war games with your grey matter because no matter what you will lose :P ..... Fuck you dont wanna end up like jon do ya ;D
There once were some bees and you took all there stuff!
You pissed off the wasp now enough is enough!!!

German

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Re: mda freebase
« Reply #35 on: October 14, 2009, 05:15:04 AM »
in reality all it does is deplete it and it takes 2 weeks to regain the stores that's it.

MDxx does not deplete your serotonin or dopamine levels. Unlike some other drugs that make your brain release these chemicals MDxx works differently. MDxx blocks the UPTAKE of these chemicals. Your brain releases them normal but MDxx attaches to your serotonin receptors that UPTAKE the chemical back into your brain so that it can not be recycled and instead the serotonin just gets quickly backed up into your bloodstream. This action damages your receptors. In rats the damage is quickly repaired, in primates the damage is permanent and can not be repaired. In humans the verdict is still out but it seems to be common knowledge amongst regular MDxx users that if you take it more then every so often that you will loose the ability to take advantage of the drug.

ribbit

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Re: mda freebase
« Reply #36 on: November 18, 2009, 03:31:09 AM »
jon you are fucking awesome i'm smoking some honey in your honor

jon

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Re: mda freebase
« Reply #37 on: November 18, 2009, 08:32:32 AM »
it's the shiz i just dip it in cigarettes amnd fire up

madprossor

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Re: mda freebase
« Reply #38 on: November 28, 2009, 08:49:47 AM »
swimp vaporized some mdma.hydrochloride a few times.

effects only last a half hour or so.  if you're the sort of person who would be tempted to re-dose at that point, then i would avoid this administration method and just eat it.  speed/adderall/dexedrine are all less habituating when taken orally than by other routes.

smoking molly is really bad for manic depressive people.  smoking just 5 or 10mg can easily kick them into a manic state lasting 12-24+ hours.  then of course another mere 5-10mg will extend the highly pleasurable manic state for another 12-24 in a viscious circle. i wonder if speed does the same thing to a manic depressive? probably so... after a week without sleep the subject may lose her sanity and accidentally narc you out.

the stuff's not weed, you're not supposed to smoke it every day for years...

<toke, puFF>

weird ass psychedelic amphetamines... people love the hell out of them, and they make people act retarded. if there was a big "happy" button in our heads that turned us into drooling, smiling, idiots when pushed, perhaps we shouldn't be pushing it all the fucking time.

none of the psychedelic amphetamines is really a top-notch psychedelic sacrament. they all have interesting effects, (DOB has some fucking *amazing* auditory hallucinations), people love the fuck out of MDxx, but they all seem to muddle the head a bit.

the phenethylamines and tryptamines/ergoloids seem mellower, and produce more interesting visuals for the most part. i don't know where i got this idea, but i feel that they're more sophisticated and "higher-tech" psychedelics than the ampetamines.

maybe people love that alpha-methyl just cause it's so bad for them... like how cats drink antifreeze...  :o

-madprossor