tell you the truth i took a long vacation and i found 5 grams i forgot about and took it over 3 days and it is just no loger any fun moral of the story is not to use too much.

When used intranasal I can go through a few grams but orally I just try to remain with the low doses.

I've abused daily for a few months on end and most of the fun has faded, not really worth it. Annoying that it remains abuseable though.

Bipolar and stimulants are a really bad combination too, that should not remain unsaid.

Charlie Sheen!? No!

I knew it Thompson,you swine,you are not dead! 

So why do you still use it, if it causes problems. And if you don't think its causing problems now, manic episodes aside, the massive quantities you are taking are going to cause major problems years down the line, if it even takes that long. Your going to completely fuck your cardiovascular system, possibly also causing pulmonary hypertension, either could easily prove fatal, or cause a stroke, fatal or otherwise.

If I were you, I would take a long, long break from MDxx and any other stimulants, use some 5HTP for a while (MDxx inhibits tryptophan hydroxylase, causing still further severe 5HT depletion) then after you have been clean for at least a week, perhaps 2, start taking some tryptophan, along with antioxidants, and after a year, if you decide to keep taking MDxx at all, stick to reasonable doses, couple of hundred milligrams perhaps. 150mg is a decent enough dose, and for those who like large amounts, perhaps another 50, or even 100 as a booster.

I consider anything more than that excessive. Personally I don't care for MDxx, the only empathogen that agrees with me I have tried, is AMT. The fake, forced, and altogether shallow, meaningless people-inclination and sociability I find not compatible with being autie. Feels....not natural, and brings out someone I am certainly not, and was never meant to be, and whats more, do not wish to be.

I am quite happy without anything causing oxytocin release. Thats one neurotransmitter I could quite easily live without completely. When I have taken MDMA, 120mg with maybe, MAYBE another 30-50mg as a booster many hours later would be absolutely enough. Although I tend to just start thinking 'why the hell did i ever bother, I wish this would just END already, for fucks cunting ratbastardlyshitting jesus H christ's twatting sake', an hour or so after dropping a dose.

Very, very rarely have I ever taken more than that, twice, I think, possibly three times, in my entire life.

Have you ever taken either of the APBs by any chance? what is it like? Toady got a free sample twice with his orders of methoxetamine of 6-APB. Is he likely to hate it?  its still languishing around in the cupboard he keeps his scripts, stash, needles, micron filters and rigs in.

He would be curious to try both MDAI and 6APBD though, as they are meant to completely lack any stimulant effects. The only stimulants that agree with him, other than camphetamine (an N-ethyl homolog of fencamfamine) are selective DARIs. Although the original ivory wave, a mixture IIRC of pentylone and MDPV was actually not bad, and in low doses, perhaps 5mg insufflated,up to maybe 10mg, 5mg up each nostril was definately enough, good for studying.

Desoxypipradrol, long duration aside is probably the best one he has tried for functional enhancement, and purely for that reason, as it is utterly, totally without euphoria, but at a very, very low dose. 250-500mcg orally is enough, 1mg would be his maximum dose. For something with a bit of a kick to it though, camphetamine is perfect. The mild opioid properties are great at smoothing out any rough edges.

Favourite stimulant all round, would be either dimethocaine or coke, at low doses. Dimethocaine is off his list though after learning of the aromatic amine in its structure, as aromatic amines are bad news toxicologically speaking (hepatotoxicity). 100-200mg of good, clean coke is just right, as far as stimulants go for the ye olde amphibian deity. Shame about dimethocaine, it was really nice actually, very smooth, clean, and at Toady's doses, completely lacking a comedown. Damn cheap too. AFAIK that aromatic amino moiety isn't necessary for binding at DAT, and if a dimethocaine analog lacking it were to be released, Tsathoggua would definately bee up for giving it a try.

He is rather pleased though with his doctor today, as in addition to his regular scripts for DHC, he now gets loprazolam and oxycontin. Started out today on 10mg oxycontin BD, although he can get it titrated up at his next appointment in 2 weeks. He is hoping to get it all the way up to 80s of course, or if possible, onto an IR formulation, He finds it so much cleaner than DHC, and finally, now he can get a nod on, just beginning to on 300mg DHC, 3mg loprazolam and to ice the cake, 30mg oxy, prepped, and micron filtered, adding water repeatedly, cooking, filtering and shooting of course, then eating the waxy remains to make sure none got away.

He has a few commitments to attend to, and then, time to kick his shoes off his weary fins, and snort a couple of oxys

Interesting post Tsathoggua,never heard about camphetamine before and can't find any references. Can you help!?

Don't know how to ask that w/o possible sounding offensive but how can ANY human being hate oxytocin effect!?
I mean...it's "the magic" that religions promisse,ideologise and family delivers soemetimes and MDMA allways!

Sure,everyone is different,I allmost can't stand coke and most dopamine releasing stuff since they inflate ego and that is not who I am,
I alos heard there are some people that can't stand opiates (I don't really belive in that,they just have happy endorphines! Try to live in pain in discomfort! :-) ) but oxytocin!?
Isn't love and loyalty like...meaning of life!? And I don't mean it in some cheesy romantic way...

Too much "anything" can cause headaches!

It isn't 6-APBD Toady has, but 6-APB.

As for oxytocin, Don't need that to fall in love, or be loyal to one's loved one. I am completely crazy about my girl, sure, she started off as sort of my stalker, but I've found myself the perfect lady. Loyalty? I am 100% hers, and nothing on earth would pursuade me to cheat on her. Not other women, not money, nothing. Being autie, I most likely have lower levels of oxytocin than the average person. Suits me just fine, I guess it might be why I really do not like MDxx or methylone. No, I do not trust lightly, but again, that suits me, if I am to trust someone, they need to earn it, which I view as the sensible way to be anyway.


I also know a lass that in all likliehood, can't produce oxytocin at all, or if so, very, very little of it, thanks to a collection of rare genetic issues, affecting amongst other things, mitochondrial function, hypothalamus and pituitary. And I know she loves her boyfriend.

There is no magic in MDMA in my experience with it, just an empty, hollow psychostimulant with other, pro-social, and unpleasant properties.

As for coke...I am not an egotistical person myself (probably because being better than everyone else, I have no need to be ....kidding of course, I am nothing of the sort, never have been, never will be), I enjoy coke, likewise dimethocaine and other DARIs. But it doesn't turn me into the pro-social, egotistical dipshit that it seems to in a lot of users. Not all, but many turn into real shitbags when they are on coke. A couple of hundred milligrams is enough. Never known anyone else who often actually weighs their lines on a scale rather than just dumping some out of the bag.

Camphetamine is the N-ethyl homolog of fencamfamine, A nor-bornyl substituted amphetamine, which has some degree of opioid effects in addition to being, in my experience, a very smooth stimulant. Most uppers I hate, including amphetamine and meth, but this one is really nice stuff. Highest I've taken it has been maybe 150mg, with a 40mg booster later, at which point, the effects were smooth, not too intense, and not pushy stimulation, didn't feel any opioid effects, but then again, not surprising considering I've been on painkillers for a good few years (just got scripted oxycontin in addition to my usual DHC) and have quite a tolerance (takes me 50mg of oxy, micron filtered and given IV to nod)

I would be curious to try oxytocin, or an oxytocin receptor agonist that is BBB penetrant, but just for the sake of seeing how the other side lives, so to speak, out of curiosity. I would in all likelyhood, not be online, and stay away from people though while it was active, if ever I tried it.

Interesting wiev!
DHC is another thing I would realy like to try! Heard it's opiate very similar to MDMA in some degree.
Unfortunately I can't metabolize codeine so I don't know will it work for me.

For me there is no better thing than MDMA,at least first few times.
Saved my life and made me better person for sure!
Yeah,you are both right,there are many people that won't give a damn for you once effects are gone
BUT there are also those friends that you made on the drug and they became your best friends for life!
Just like brothers in arms! It's special kind of friendship you can count on even in hardest moment,especialy
if you were friends before. For me,this is all that matters!

I personaly think that at least formation of loyalty and love,as I know it,is impossible w/o oxytocin.
You NEED to have at least some.
I think oxytocin is a "cupid's dart",that thing that makes you feel fanatica about someone or something (person,ideology,religion...) and forget about all of it's flaws. It can make life so much better but also so much worse!
I would,of course,like to know something that blocks the damn thing too!
Falling in love that can't be realized with someone/something is probably one of the most painfull
and traumatic events in life. Sure! With enough reason and self control you can overcome it but it's
not much better than going cold turkey on opiates!

i agree, i don't understand how anyone can say they don't enjoy the oxytocin effect of mdma but everyone's different of course.  i've heard some people say that mdma feels too forced.  in my opinion i disagree, it makes me feel more alive than any other drug by far.  but to each their own.

in regards to dihydrocodeine, it's not available in the US but i've ordered it from the UK a couple times awhile back and i really liked it.  it was exactly what you'd expect by looking at the molecule, a hybrid between codeine and hydrocodone.  dosage-wise you have to dose high like codeine (DHC is slightly more potent) and DHC does have the annoying brutal histamine response that codeine has but not nearly as bad.  all opiates i've ever taken have some sort of histamine response at the right dose but as we all know, codeine is notorious for its histamine activity.  the feel of DHC itself feels more like hydrocodone than codeine.  it has a more stimulating feel like hydrocodone and the nod is unique in itself but i'd compare it closest to that of hydrocodone's nod, but it has the slight warmth of codeine/morphine.  i found DHC to have a wonderful mood boost effect and, like i said, energetic.  there is kind of a fine-line between getting a nice nod on DHC and getting the nasty codeine-esque histamine reaction.  however DHC gives you more leeway before the histamine response than codeine does, i can't get a nod on codeine but i've definitely gotten horrendous itching and nausea from high dose codeine.

you mention DHC being very similar to mdma in some degree, i've never had any opiates i can compare to mdma even in the slightest bit although if i had to make a choice i'd say demerol feels closest like mdma out of all the opiates i've tried, but even demerol feels nothing like mdma.

if you read up on the internet you'll find a wide array of opinions on DHC but my opinion is that it's very worthwhile and is by far my favorite "weak opiate" hands down.  for the most part i'd pick hydrocodone over DHC but on some occasions i'd prefer DHC to hydrocodone depending on my mood and what i'm looking for exactly.  i get energy on both of them, i get better focus on hydrocodone but i get better all-around physical euphoria from DHC.  i think at around 90mg i felt a nice, strong mood boost.  at twice that dose i begin to feel a hydrocodone-esque energy and motivation.  at around 300mg i get a nice nod on DHC and at too much higher than that is where the histamine activity occurs for me.  i can dose over 300mg over a long period of time with no histamine-related problem but i'm referring to taking it all at once.  i wish DHC was available here in the US, like i said it's by far the best weak opiate around IMHO.  darvocet is pretty much like placebo (and toxic), codeine is ok but not nearly as good as DHC, tramadol is the worst fucking opiate-ish drug i've ever taken and would rather endure oxycodone withdrawals cold turkey rather than take tramadol to alleviate the hell of w/d's - that's how much i hate tramadol.

Had that experience, doctor ignorant about pain relief trying to get me to accept tramadol as an apparent stronger opioid than my DHC. Nasty stuff. In the end I saw my regular doc and got oxy added to my regular DHC script, which suits me far better (and to a degree, does something for my buggered up knee, although the starting dose doesn't do much at all...doctors in the UK seem far too conservative, especially when considered, the patient is opioid tolerant already through being a chronic pain patient, when it comes to prescribing opioids that aren't piss-weak.)

DHC is nothing AT ALL like MDMA in my experience, and I've been on the stuff since fuck knows when. Wasn't anything like it when I was opioid-naiive, either. It was, along with codeine and oral morphine (its OTC here in limited doses in a proprietary cough product) the first opioid I ever tried, IIRC. Wouldn't still be taking it, if it were anything like MDxx

DHC, unlike codeine, is active in its own right, indeed AFAIK it is the main active drug when taken, very, very little, gets converted to dihydromorphine.