Author Topic: loperamide + Li = aryllithium + o2 = phenol enhacing mu recetor affinity  (Read 106 times)

jon

  • Foundress Queen
  • *****
  • Posts: 1,883
loperamide + Li = aryllithium + o2 = phenol enhacing mu recetor affinity
« on: December 16, 2009, 08:08:22 PM »
you know this idea came into my retarded brain like a light bulb went off.
how about taking this
http://en.wikipedia.org/wiki/Loperamide

and forming it's aryllithium the tert alhol would also form an alkoxide too.
treat with oxygen to get the phenol derivative also the alkoxide can be reacted with proionyl chloride if this were done we'd have a diester.
what do you guys think?

http://books.google.com/books?id=cm5s84-GeKMC&pg=PA871&lpg=PA871&dq=aryllithium+phenol&source=bl&ots=e4QB4brct-&sig=pKehV8USdVybNor-ZKzfKRgnS7U&hl=en&ei=BHspS-KxOY2-NsXd6YIM&sa=X&oi=book_result&ct=result&resnum=2&ved=0CAwQ6AEwATgU#v=onepage&q=aryllithium%20phenol&f=false
« Last Edit: December 17, 2009, 12:31:02 AM by jon »