Cocaine synthesis?

wolframine · Tue Jun 07, 2005 12:02 am

Hello new and old bees!

Why is there so few cocain synthesis to look up? I dreamt about the synthesis of SR(+-) 2-carbomethoxy-3-tropinone from tropinone with NaH as a 60 % mixture with petroleum. The synthesis was very simple to do and gave nice yields on a 100 g batch, with only 4 h refluks in syklohexane. Is there a bether synthesis from tropinone that give only the wanted stereoisomer? And is tropinone, dimethylcarbonate and benzoic anhydride awailable from aldrich or acros without fill in all this forms to the government, and in what quantity? Twisted Evil

icecool · Insistent Chemist

I would suggest you read around here a bit more, and learn your self to write proper english.
And no you can't just mail aldrich and acros if they could send you some tropinone and benzoic anhydride etc.
First try to make GHB or amphetamine or the like and then 2CB and THEN try cocaine...

stratosphere · Tue Jun 07, 2005 5:29 pm

i think i would attempt the "cocaine light" synthesis on rhodium before real cocaine as its simpler and 40X stronger

Richy · Thu Jun 09, 2005 2:31 pm

Ecognine may be used in the synthesis of even more potent phenyltropanes, up to 64x the potency of cocaine and many times longer lasting in rodent subjects.

Is there a practical means of synthesising ecognine (seing as its closely related to cocaine itself and is most likely suspect)?