Argyreia nervosa - Hawaiian Baby Woodrose seeds

java · Consumer

subject: Argyreia nervosa - Hawaiian Baby Woodrose seeds

moecat......excellent post, and remember no respond so far doesn't mean no one is reading, my experience with baby wood rose was the crushing and separation using colummn chromatography I could have used this reference material from your study then, but someone else is learning from your efforts, I for one.........java

moecat · Sun Feb 20, 2005 12:15 am

moecat · Mon Feb 21, 2005 10:55 am

MistaMiyagi · Dream Team

(this thread will be moved out of the methods forum as it is not a synth or procedure but rather analytical results targeting a specific class of compound)

moecat · Fri Feb 25, 2005 9:21 am

moecat · Fri Feb 25, 2005 9:23 am

Vitriodor · Sat Feb 26, 2005 7:29 am

Recreational use of Ergoline Alkaloids from Argyreia Nervosa"
William E. Shawcross
Journal of Psychedelic Drugs Vol. 15(4) Oct-Dec 1983

CHEMISTRY AND EFFECT OF THE SEEDS
The Hawaiian baby woodrose entered the drug scene in 1965 with the
publication of a paper in "Science" entitled "Ergoline Alkaloids in Tropical
Wood Roses" by Hylin and Watson. The wide circulation of this journal assured
thorough dissemination of the information they presented. They wrote, "The
possible health and legal problems associated with the presence of similar
compounds in commercially cultivated plants led us to examine the ornamental
wood roses, Ipomoea tuberosa and Argyreia nervosa, both common Hawaiian crops
that have assumed commerical importance as components of [the] dried tropical
flower industry." Comparing the seeds of these two plants with those of the
morning glory varieties Pearly Gates and Heavenly Blue, they found the
following yield of alkaloids (mg of alkaloid/g of seed material):

Heavenly Blue 0.813
Pearly Gates 0.423
I. tuberosa [None]
A. nervosa 3.050

The seed of A. nervosa is the best plant source of ergoline alkaloids
discovered; it contains approximately 3 mg of alkaloidal material per gram of
seed. Approximately one-eighth of this is lysergamide.

Hylin and Watson found the major alkaloidal constituents in A. nervosa seeds to
be ergine (780 mcg/g of fresh seed) and isoergine and penniclavine (555 mcg).

=============================================

From "The Botanical and Chemical Distribution of Hallucinogens"
Richard Evans Schultes, PhD.
Journal of Psychedlic Drugs Vol.9(No.3) Jul-Sep 1977

The main psychotomimetic constituent of the seeds of both species
[Ipomoea tricolor & Rivea corymbosa] are ergine (d-delta-lysergic acid
amide) and isoergine (d-delta-isolysergic acid amide) which occur together
with minor alkaloids: chanoclavine, elymoclavine, and lysergol.
Ergometrine appears to be present in the seeds of I. violacea, but
absent in R. corymbosa. The total alkaloid content of R. corymbosa seed
is 0.012% ; of I. violacea, 0.06% - and, indeed Indians use smaller quantities
of the latter than of the former.

I. violacea, often referred to by it's synonyms I. rubro-caerulea and
I. tricolor, is represented in horticulture by a number of "varieties,"
such as: Heavenly Blue, Pearly Gates, Flying Saucers, Wedding Bells,
Summer Skies, and Blue Stars - all of which contain the hallucinogenic
ergot alkaloids.

==============================================

"Indole Alkaloids In Plant Hallucinogens" Richard Evans Schultes, PhD.
Journal of Psychedelic Drugs Vol.8(No.1) Jan-Mar 1976

"The main constituent of the seeds of Rivea corymbosa is ergine or d-lysergic
acid amide. Minor alkaloids present are the related d-isolysergic acid amide
(isoergine), chanoclavine, elymoclavine and lysergol. The seeds of Ipomoea
violacea have a similar composition, but instead of lysergol, they have
ergometrine (ergonovine). Later, very minor amounts of two alkaloids
ergometrinine and penniclavine - were found in I. violacea by chromatography.
the total alkaloid content of the seeds of Ipomoea violacea is approximately
five times as great as that of the seeds of Rivea corymbosa: 0.06% in the
former; 0.012% in the latter. This difference in the alkaloid content
explains why Indians employ smaller doses of seeds of the Ipomoea than of the
Rivea.

==============================================

"Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants"
Jose Luis Diaz M.D.
Journal of Psychedelic Drugs Vol. 11(1-2) Jan-Jun 1979

Seeds of various Morning Glories contain
Ergolines: ergine,isoergine,ergonovine
Glucosides: turbicoryn [apparently in Rivea corymbosa only]

called Tlitlitzen (Aztec word for "The Divine Black One")
to the Aztecs, Black is a "hot" color,
a property of psychotropics associated with light

==============================================

"Medicinal Chemistry" Part II, Third edition
Article: "Hallucinogenic Agents" Alfred Burger

The investigation of a third magic drug, ololiuqui, took an unexpected turn.
Ololiuqui [also called coaxihuitl (Aztec), badoh (Zapotec), yucu-yaha
(Mixtec), xtabentum (Maya), flor de la Virgen, yerba del las serpientes
(Spanish), snake plant, etc.] is a green twining herb of three species of the
wild American morning glory, with long white blossoms and round brown (badoh)
or black (badoh negro) seeds. The priests ate this plant to induce visions
and satanic hallucinations, believed to have been messages from the gods. The
patients of professional soothsayers (piuleros) drank alcoholic beverages
(pulque, aguardiente, etc.) containing the crushed seeds; in the ensuing
sleepy-narcotic state they revealed information about themselves that the
piulero could use to forecast the client's future or prescribe for his
illness. The brown seeds have been identified as Rivea corymbosa; the black
seeds, as Ipomoea violacea.

=============================================

"Medical Botany, Plants Affecting Man's Health" Lewis & Evans-Lewis

Family: Convolvulaceae
Species: Ipomoea violacea
Name: Morning Glory
Active Hallucinogens: D-Lysergic acid amide (ergoline)
other "ergot" alkaloids may be active
Comments: Used in Mexico as a hallucinogen

=============================================

"Burger's Medicinal Chemistry" Fourth Edition, Volume III
Chapter: "Hallucinogens" Alexander Shulgin

Composition, % of total alkaloids present
-----------------------------------------
Compound R. corymbosa I. violacea
--------------- ---------------- ----------------------
Ergine (LA-111) 54, 48 58, 10-16, 5-10 *
Isoergine 17, 35 8, 18-26, 9-17 *
Ergometrine 8
Elymoclavine 4 4
Chanoclavine 4 4
Lysergol 4

Total Alkaloids .012, .04 .06, .04-.08, .02-.04
(% of dry weight
of seeds)

* Numbers separated by commas represent results from various sources.