E-Books available for download....

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PURIFICATION OF LABORATORY CHEMICALS
Armarego, Wilfred, L.F.; Chai, Christina, L.L.
http://rapidshare.de/files/1146245/Purification_of_Laboratory_Chemicals_-_5th_Edition.pdf.html

Description:
Outlines for chemists, biochemists and other scientists procedures and processes for purifying over 4000 organic and 750 inorganic and organometallic commercially available chemicals.

Note : thanks to the members of sciencemadness that made it available.

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THE ANALYSIS OF CONTROLLED SUBSTANCES
Michael D. Cole
http://rapidshare.de/files/1156714/the_analysis_of_controlled_substances.pdf.html

Summary:
"This series of books provides coverage of all of the major analytical techniques and their application in the most important areas of physical, life and materials science. Each text is presented in an open learning/distance learning style, in which the learning objectives are clearly identified. The reader's understanding of the material is constantly evaluated by the use of self-assessment and discussion questions. Series Editor: David J. Ando. It is now recognized that, in order to ensure the validity of a forensic science analysis, a number of criteria need to be met. These include the following: The sample under investigation is suitable for the analysis being carried out. The analytical procedure adopted will answer the particular question(s) being asked, for example, with respect to identification, quantification and profiling (comparison of samples). The data obtained are both correctly recorded and interpreted. The findings are accurately reported. The aim of this text is to provide an understanding into the analysis of drugs of abuse within the context of their control, an appreciation of the different techniques that can be employed for drug analysis and the reasons for their use. In this book, the major classes of drugs of abuse are addressed, the analysis of which follows a systematic framework, including description, presumptive testing, thin layer chromatography, instrumental methods and data analysis. Throughout the text, regular questions and answers are used to further develop an understanding of the processes being employed. This book will appeal to both undergraduate and postgraduate students of forensic science, as well as those practitioners who are new in post or receiving additional or refresher training. It should also be of benefit to those who are studying controlled substances as broadening courses in other scientific disciplines. "

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Compendium of Organic Synthetic Methods
Michael B Smith
http://rapidshare.de/files/1187540/Compendium_of_Organic_Synthesis.rar.html

About the book

New protocols for functional group transformations and carbon-carbon bond-forming reactions Organic transformations are the heart of synthetic organic chemistry. The Compendium of Organic Synthetic Methods series facilitates the search for the most useful functional group transformations in organic chemistry. Compendium of Organic Synthetic Methods, Volume 10 provides quick access to proven protocols for the newest, most useful reactions and transformations. It contains both functional group transformations and carbon-carbon bond-forming reactions, as well as a chapter devoted exclusively to difunctional compounds. The Compendium series provides a handy reference and a valuable tool to the working organic chemist, allowing a quick check of known organic transformations. Author Michael Smith adheres to the series's tradition of employing strict criteria for inclusion of reactions, including real synthetic utility and reagents readily available or easily prepared and handled in the laboratory. Among many other subjects, Volume 10 covers: *Alkynes *Aldehydes *Amines *Esters *Halides and sulfonates *Ketones *Nitriles *Oxides As in all the previous Compendium volumes, the classification schemes used allow for quick and easy reference and information retrieval. Chemical transformations are classified by the reacting functional group of the starting material and then by the functional group formed. Helpful indices are provided for both monofunctional and difunctional compounds as an efficient means of guidance to specific classes of transformations. Compendium of Organic Synthetic Methods, Volume 10 is an unparalleled source of information on the methods, reactions, and transformations in contemporary organic chemistry for the working chemist and student.

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Practical Organic Chemistry
Fredrick Mann
PDF

Description

A clear and reliable guide to students of practical organic chemistry at the undergraduate and postgraduate levels. This edition’s special emphasis is on semi micro methods and modern techniques and reactions.

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Cycloadditions Reactions in Organic Synthesis
edited by S Kobayashi &K A Jorgensen

http://rapidshare.de/files/1191872/Cycloaddition.zip.html
Description
Cycloaddition reactions are among the most important tools for synthesis in organic chemistry, since these reactions are vital to the modern synthesis of natural products and biologically active substances.

Metal catalysis plays an increasingly important role in these reactions, often allowing several stereocenters to be selectively created and integrated in the target molecules. Kobayashi and Jorgensen's handbook provides numerous examples of metal-catalyzed reactions, including [2+1], [3+2] and [4+2] cycloadditions. Important reactions such as carbo- and hetero-Diels-Alder, carbocyclic, cyclopropanation and 1,3-dipolar cycloaddition reactions are discussed. A large number of experimental procedures gives a concrete idea of the use of metal-catalyzed cycloaddition reactions in modern synthesis.

The book is aimed at chemists in industry or academia, who want to effectively use cycloadditions in their work

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The Diels-Alder Reaction Selected Practical Methods
Edited by Francesco Fringuelli & Aldo Taticchi

http://rapidshare.de/files/1191294/Diels-Alder.zip.html

Description
This is the first book to collect together 70 years worth of experimental procedures that have been developed to perfom the Diels-Alder reaction. It begins with the fundamental principles and contains numerous graphical abstracts to present the basic concepts in a concise and pictorial way. Covering the theory and synthetic applications of the experimental methods it describes the procedures and techniques and includes reports on industrial applications.

Illustrates the fundamental principles and summarises experimental methods used to carry out the Diels-Alder reaction
Contains physical and catalytic methods to enhance the selectivity of the Diels-Alder reaction
Includes procedures for cycloaddition accomplished in conventional and unconventional media
Outlines the practical procedures
Focuses on clean syntheses and green chemistry
Provides a single source for relevant information and includes over 1,000 references
The Diels-Alder reaction mechanism was first published in 1928 and in the last 70 years has become the most commonly used and studied mechanism in organic chemistry.

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Drug Targeting Organ Specific Strategies
G Molema, DKF Meijer

http://rapidshare.de/files/1191982/Drug_Targeting.zip.html

Description

This thoroughly application-oriented book gives comprehensive answers to many questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic.

The book goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The main focus remains on the practical aspect and successful application of the method in drug targeting.

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Chiral Separation Techniques
Edited by G.Subramanian

http://rapidshare.de/files/1192250/Chiral.zip.html

Description

This is a completely revised and updated sequel to 'A Practical Approach to Chiral Separations by Liquid Chromatography' by the same editor. The scope has been extended to further chiral separation techniques like electrophoresis, membrane separations, or biological assays. More emphasis is put on preparative separation techniques.

From reviews of the previous edition:
"A team of experts from academic and industrial laboratories throughout the world have compiled their findings and experience to make this book an exceptionally timely and unique contribution to the field" --European Journal of Drug Metabolism

"The dense mass of information contained in this book will make it a valuable resource..." --Chemical Engineering Research "... this is a worthwhile addition to the expanding chiral literature and the book should be of value to those working in this field" --The Analyst

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Catalytic Heterofunctionalization
A Togni H Gruyzmacher

http://rapidshare.de/files/1191925/Heterofunctionalization.zip.html

Description

Catalytic heterofunctionalization is now an important area of research in homogeneous catalysis, allowing the formation of a wide variety of bonds between carbon and other elements by adding compounds to alkenes and alkines. It is the catalysis of these key additions that makes this type of synthesis most effective.
In this first handbook on the subject, well-known authors and editors present all the modern synthetic methods including hydroamination, hydrosilylation, hydrozirconation, hydroalumination, hydroboration and
hydrophosphination.
An indispensable source for every researcher and practitioner of homogeneous catalysis as well as for all synthetic organic chemists in academia and industry.

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Common Fragrance and Flavor Materials
Kurt Bauer Dorothea Garbe Horst Surburg

http://rapidshare.de/files/1191267/Fragrance.zip.html

Description

Get a good start in flavor and fragrance chemistry!

This book presents a survey of those natural and synthetic fragrance and flavor materials which are commercially available, produced and used on a relatively large scale and which are important ingredients for the creation of fragrance and flavor compositions because of their specific sensory characteristics, e.g., smell, taste. It provides information on their properties, methods employed in their manufacture, and their areas of application.

'...The excellent and concise introduction to this unique industry is followed by extensive information on nearly 500 of the most used fragrance and flavor compounds. Names, molecular formula, physical data, odor and flavor descriptions, uses, and a number of processes for the larger scale production of chemicals are all included. Successive chapters deal with essential oils, animal secretions, quality control, toxicology and literature. The formula, name and CAS registry number index are an invaluable and timely addition.' - Parfumer and Flavorist

'...Data that would normally have to be selected from many different books are available in one source with this book...with over 800 citations throughout the text, this is a nearly inexhaustible source of information.' - Euromaterials

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Homogenous Catalysis; Mechanisms and Industrial Applications
Sumit Bhaduri Doble Mukesh

http://rapidshare.de/files/1191244/Homogeneous_Catalysis.zip.html

Description

Homogeneous catalysis made easy through real-world examples and illustrations.

The field of homogeneous catalysis has grown dramatically over the past decade, boasting many new applications in the chemical, fine chemical, and pharmaceutical industries. This timely work offers a unified, easy-to-understand treatment of this challenging area of chemistry. With a practical emphasis and a thorough, selective survey of current literature, the authors present homogeneous catalytic reactions proven successful in industrial applications-illustrating both the mechanistic principles and illuminating new areas of academic and industrial research. An ideal self-study guide for inorganic chemists seeking to gain entry into the field as well as a much-needed reference for industry professionals, Homogeneous Catalysis: Mechanisms and Industrial Applications features:

Clear discussions of the fundamental chemical and chemical engineering concepts relevant to homogeneous catalysis.
Important examples from selected industrial processes.
Extensive references to cutting-edge research with application potential (through March of 1999).
Many tables and more than 100 illustrations to help explain difficult concepts.
Problems of variable complexities accompanying each chapter

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Nitration And Aromatic Reactivity
JG Hoggett RB Moodie JR Penton K Schofield
http://rapidshare.de/files/1191188/Hoggett__J_1_._G._-_Nitration_and_aromatic_reactivity.pdf.html

Preface

Ten years ago we became interested in the possibility of using nitration
as a process with which to study the reactivity of hetero-aromatic
compounds towards electrophilic substitution. The choice of nitration
was determined by the consideration that its mechanism was probably
better understood than that of any other electrophilic substitution.
Others also were pursuing the same objective, and a considerable
amount of information has now been compiled.
This work, and that which has been reported in the past decade about
the general topic of nitration, has advanced our knowledge appreciably,
and has also revealed some gaps in our understanding of the subject.
This book reviews the present position, and collects together much detailed
information about quantitative aspects of nitration from the
extensive research literature on the subject. In offering it we should like
to express our gratitude to Drs R. G. Coombes, J. T. Gleghorn,
S. R. Hartshorn, E. A. Qureshi, M. J. Thompson and M. J. Williamson,
who, as well as our co-authors, have worked with us on nitration.

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Principles of Biochemistry
Lehringer

http://rapidshare.de/files/2785553/Principles_of_BiochemistryLehringer_Biochem.djvu.html
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or..........,

http://213.8.170.243/books_online/August2005/Science%20-%20Lehninger%20Principles%20of%20Biochemistry%204th.rar

Note: thanks to the watcher for the securing of the book ans ayush for the refresh link...

rev. 06-03-05

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Indoles
R.J. Sundberg

http://rapidshare.de/files/1226205/indoles.pdf.html

Product Description

Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and by the biological activity of many indole derivatives, of both natural and synthetic origin. This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates information available on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicability and variations in methodology. The organisation of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials.

From the Publisher:
Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and by the biological activity of many indole derivatives, of both natural and synthetic origin. This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates information available on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicability and variations in methodology. The organisation of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials.

ezeK · Fri Apr 15, 2005 5:55 pm

AMPHETAMINE-TYPE STIMULANTS
A GLOBAL REVIEW
Prepared by UNDCP at the request
of the Commission on Narcotic Drugs

http://rapidshare.de/files/1276340/amphetamine.stimulants.pdf.html

Abstract

In the ever-widening discourse on substance abuse, it is frequently asserted that the key problem of the future will be associated with what are commonly known as synthetic drugs. The present paper is an attempt to assess the validity of this proposition. The subject is too vast and intricate to cover in a single review, but guidance for achieving a manageable focus can be found in two areas: the level of international consensus in defining a critical area and the nature of the substances themselves. With regard to defining the key area, the Economic and Social Council, reflecting the common concerns of many States Members of the United Nations, adopted resolution 1995/20 calling for a thorough study of psychotropic substances, particularly stimulants and their precursors. Even the category "stimulants", however, is a very wide one, covering a large range of substances whose principal pharmacological effect is to stimulate the central nervous system of the body. There is some pragmatic justification, detailed in Table 1, in narrowing this category down to a group of substances that are similar, not only in their pharmacological effect but also in chemical structure: the amphetamine-type stimulants (abbreviated, throughout this review, as ATS).