synthetikal.com Forum Index


Built by the Community for the Community
 Forum IndexForums 
 
   Rhodium Chemistry ArchiveRhodium   The ArcHiveThe Hive   Shop   ProfileProfile   Log inLog in   RegisterRegister 
AMT from Tryptophan?
Page 1 of 1
Post new topic   Reply to topic    synthetikal.com Forum Index -> Tryptamines
Author Message
capricorn

Joined: 22 Mar 2005
Posts: 9
275.42 Points
View Single Post2577
AMT from Tryptophan?

 Fri Apr 01, 2005 4:56 am		 Reply with quote
If one were to react tryptophan and formaldehyd in the akabori reaction insted of benzaldehyd and alanin as described in another thred, one should get AMT with an OH gruop at the a-methyl carbon (if its just straight forward and no other rules apply, such as cyclization)
If it then could be possible to reduce the OH group some way (HI/RP?) one should end up with AMT.

Just some thoughts on another application of the akabori reaction...does it seem posible?
Back to top
CherrieBaby
chouchou
Joined: 01 Mar 2005
Posts: 67
3070.02 Points
View Single Post2588

 Fri Apr 01, 2005 8:41 am		 Reply with quote
That won't work. The Akabori rxn works with aromatic aldehydes not just any old aldehyde.
Back to top
Display posts from previous:   
Post new topic   Reply to topic    synthetikal.com Forum Index -> Tryptamines All times are GMT + 5.5 Hours
Page 1 of 1

 



Powered by phpBB 2.0.11 © 2001, 2002 phpBB Group

Igloo Theme Version 1.0 :: Created By: Andrew Charron