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syringes :)
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brain
Linguist Extraordinaire
Joined: 08 Mar 2005
Posts: 143
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syringes :)

 Mon May 09, 2005 8:48 pm		 Reply with quote
Im wondering, what kind of H2O can i use for injections, destilled? fisiological salts solution? or mabey the normal drink water [sterylized] will be fine?
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mk-1

Joined: 20 Feb 2005
Posts: 86
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re: syringes :)

 Tue May 10, 2005 2:33 am		 Reply with quote
saline solution (0.9% salt) is what used for injections in clinical procedures
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brain
Linguist Extraordinaire
Joined: 08 Mar 2005
Posts: 143
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re: syringes :)

 Tue May 10, 2005 12:52 pm		 Reply with quote
yes because its isotonic, but if you dissolwe in it substance it will be hipertonic Smile

-and not ewery substance can be soluble in "salt" solution Smile
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methyl_ethyl
Riedel De Haen
Joined: 18 Feb 2005
Posts: 107
Location: Estonia
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Re: re: syringes :)

 Sat May 14, 2005 5:32 am		 Reply with quote
brain wrote:
yes because its isotonic, but if you dissolwe in it substance it will be hipertonic Smile

-and not ewery substance can be soluble in "salt" solution Smile


WFI (water for injection) should be able to be sourced quite easily. It contains no buffers, just water that has been assayed to meet the stringent specifications of an injectable without any added salts or what not. It should be noted that most WFI preparations have a pH of ~5.2 IIRC, so keep this in mind when preparing whatever it is you are preparing.

The WFI we use on the industial scale is just Water that has gone through an RO loop an then "distilled" using a large still / condensor apparatus. The resultant product is then tested for endotoxin, sterility, and membrane filtration for dtermination of microbial growth.

I apologize to any true microbiologists out there, my vocabulary pertaining to micro topics is at best, shite worthy.

So if 0.9% Saline solution will not harbor the drug you plan on injecting perhaps WFI will be a possible alternative.

regards,

methyl_ethyl
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pikkolo_z

Joined: 16 Jun 2005
Posts: 26
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re: syringes :)

 Fri Jun 17, 2005 7:58 am		 Reply with quote
most bottled water works fine . dont know about how safe but it works no ill side affects yet . tap water no way .
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