Author Topic: The Pharma Sutra (Read 159 times)

embezzler · « **on:** August 22, 2010, 07:18:02 PM »

Its in the title, I was wondering what you guys would recommend for increasing pleasure in the sack

No need to mention MA mind.

I like a bit of weed myself, vodka too. Have some strychnine lying around that I have heard is supposed to be nice.

MDMA is nice but it is kind of hard to concentrate and to , erm... maintain. Id you catch my drift.

Tried the psylocibin once before and never again, impossible to perform when you are seeing your partners face transform into a panther.

So any suggestions?

Quantum Dude · « **Reply #1 on:** August 22, 2010, 08:07:23 PM »

Hehehe catchy thread name I gotta say

Well it all depends on the definition of pleasure one has I guess. For me its to last longer without cumming and finally, when reaching climax, busting an incredibly satisfying nut

.

For this I have found that SSRIs, such as Paroxetine or Escitalopram, were the absolute best solution. The difference is simply amazing how naturally aroused you can get and yet really delay climax. Of course, SSRIs have their shares of unpleasant side-effects which could seriously influence theyre choice as a sexual performance enhancer.

QD

Vesp · « **Reply #2 on:** August 22, 2010, 08:13:02 PM »

Yohimbine is supposed to do something, and there is also amyl nitrite or the likes -- not to sure how either of them works but I believe both of them serve the purpose of increasing pleasure.

http://en.wikipedia.org/wiki/Yohimbine
http://en.wikipedia.org/wiki/Amyl_nitrite#Physiological_effects
http://en.wikipedia.org/wiki/Poppers

*I think poppers, amyl nitrite, etc are mostly beneficial to woman and homosexuals, though, I don't know - never spent much time reading about them.

I've always thought it would be a good idea to come up with a drug that allows males to have multiple orgasms.
From my understanding oxytocin (though, it might have been something else.. but nothing is coming to mind) is released in high amounts at orgasm and than stays present for a while - which some how prevents orgasm, only after a while when the oxytocin has been metabolized, or whatever is it than possible for another orgasm. Has something to do with the refectory period.

http://en.wikipedia.org/wiki/Refractory_period_%28sex%29

If there were a drug that could increase its metabolism, or decrease its output in a safe way -- perhaps that could be of use -- I am not sure. It isn't really something I spend a lot of time thinking about.

embezzler · « **Reply #3 on:** August 22, 2010, 08:39:22 PM »

The Yohimbe, at least the pharmaceutical grade, seems difficult to come by and since I have had panic disorder in the past I am in no rush to run the risk again.

I have a bottle of amly nitrate but its a timing thing really, you only use it right at the end and then you gotta interrupt things to do it... kinda like using a rubber

Q-D the SSRI's may be an alright idea. I experimented a bit with Fluoxetine before during a synthesis of the same and found that while arousal was possible climax was not. It may be worth a revisit. I think they may not be great for males though as they damage sperm in vivo. That is the case with Fluoxetine (Prozac) in any case. I'm sure short time use would be OK so Ill see if my mate will donate a few of his pills.

I know the FDA gave it the thumbs down but has anyone experimented with Flibanserin? It was touted as famale viagra before clinical trials but doesn't seem to have been sufficiently more useful when compared to a placebo. Its activity was picked up on due to anecdotal evidence so there must be something to it. may be more obtainable now that it doesn't have the commercial viability it once had.

http://en.wikipedia.org/wiki/Flibanserin

Quantum Dude · « **Reply #4 on:** August 22, 2010, 08:54:22 PM »

Quote from: embezzler on August 22, 2010, 08:39:22 PM

I experimented a bit with Fluoxetine before during a synthesis of the same and found that while arousal was possible climax was not. It may be worth a revisit. I think they may not be great for males though as they damage sperm in vivo. That is the case with Fluoxetine (Prozac) in any case. I'm sure short time use would be OK so Ill see if my mate will donate a few of his pills.

I sure am aware of this issue and can verify hands-down that Escitalopram is reported to overcum (pun intended) this. For the sperm count issue, I found it beneficial as I sure dont want to add my genes to this sorry-ass pool that we call humanity

.

Satan · « **Reply #5 on:** August 22, 2010, 09:08:39 PM »

http://sexanddrugs.info/

Sedit · « **Reply #6 on:** August 22, 2010, 09:33:11 PM »

Escitalopram is pretty cool at first. Makes you feel like a god damn porn star however it gets old really quick. The ability to orgasm is greatly decreased while sensitivity does not appear to be lowered in anyway.

salat · « **Reply #7 on:** August 22, 2010, 10:47:13 PM »

Herbal aphrodesiacs is one of my favorite research topics. I haven't tried all the ones I've got, but I agree Yohimbe can cause anxiety attacks.

We sometimes scene(have sex of various sorts/role play etc) for days at a time so knowing what can be used to keep the mood going is good to know.

The most effective ones I have found are catuaba, muira puama, and mucuna puriens. You can get catuaba and muira puama very reasonably from Mountain Rose Botanicals. (The shaman type shops sell it for outrageous prices comparitively.) You can get mucuna puriens powder from Starwest Botanicals.

The Mucuna has L-dopa in it and when we are scening I will take a 500 mg capsule a couple of times a day. Too much can make me goofy(ier) headed. We've been taking it for years without any ill effect.

Catuaba
There are several trees used to produce catuaba - I use Trichilia catigua but want to try the Erythroxylum catuaba. I just haven't been able to locate it in cut/sifted form. I prefer to grind it at cooking time - more options chemistry wise. I soxhlet it with EtOH or vodka and then evap off the solvent.

Muira Puama This one I buy the powder for because I haven't had time to build a mill. The bark is really tough. I do an old fashioned percolation with alcohol. I've tried soxhlet but not sure if it made any difference keeping it cool. I evap off the alcohol under vacuum.

I mix the catuaba 50/50 and and add ascorbic acid take it with some arginine. The mixture is sold in Brazil and some studies indicated it was a good antidepressant. The catuaba increases periperal circulation and you get some nice chills off it. I'm not sure what the contribution of the muira puama is (possibly anti-anxiety), but it works better together than singly.

I've got a bunch in the queue to try out. Epimedium has icariin in it which has a similar effect to viagra, I just haven't done the work to figure out the best extraction methodology.

The ssri's are real killers of your sex drive because they boost seretonin too much, you want more dopamine for sex.

salat

Quantum Dude · « **Reply #8 on:** August 22, 2010, 10:54:07 PM »

Quote from: salat on August 22, 2010, 10:47:13 PM

The ssri's are real killers of your sex drive because they boost seretonin too much, you want more dopamine for sex.

Thats highly theoretical and surely does not apply to everyone.

Vanadium · « **Reply #9 on:** August 22, 2010, 11:01:34 PM »

GHB/GBL

http://members.tripod.com/aleister_crowley/BetterSex.html

Vesp · « **Reply #10 on:** August 22, 2010, 11:03:55 PM »

I have seen the Yohimbe in energy drinks sold at 7/11 as well and by pressurized oxygen cans for reactional breathing - Not to sure if O2 has any potential here, but it is strange for such a common store to sell.

Tsathoggua · « **Reply #11 on:** August 23, 2010, 01:51:28 AM »

Recreational breathing? damn, ten years from now, you better watch you aren't getting your door kicked in to check you don't have any evil equipment only criminals and the insane would posess, or list 1 precursors such as dihydrogen monoxide, graphite electrodes, power supplies...

Sooner or later those bastards at the DEA will have you all having to show ID, and be limited to three packs of 9 volt batteries or their equivalent per month.

salat · « **Reply #12 on:** August 23, 2010, 02:23:35 PM »

Quote from: Quantum Dude on August 22, 2010, 10:54:07 PM

Quote from: salat on August 22, 2010, 10:47:13 PM

The ssri's are real killers of your sex drive because they boost seretonin too much, you want more dopamine for sex.

Thats highly theoretical and surely does not apply to everyone.

Which part is highly theoretical? The SSRI causing sexual problems or the dopamine involved in sexual arousal?

I'm sure nothing applies to everyone.

I read a lot of pubmed and my mind gets boggled at the conclusions they reach from making poor mice drown. I don't always do a good job of questioning what I read - still a bit programmed to believe scientists. They always sound so sure about their pronouncements. And I have a really horrible time trying to remember where I read what - even if I save it - I got literally gigabytes of saved stuff on my hard drive and not much in the way of organization and my house is littered with papers. I'm retiring October (early I'm only 50) and maybe I can get my private wiki up to start doing a better job of tracking this stuff. I get hyperfocused and on a trail of information - form hypothesis and promptly forget how I got there - leaving the very real need to verify my facts undone.

I recall reading that you wanted the balance of seretonin to be low in comparison to dopamine for increasing sex drive.

My personal experience is SSRI's suck (was on Effexor for 10 years) and kill your ability to orgasm. As in can't even masterbate dead! Adderall is much more pro sex.

salat

Quantum Dude · « **Reply #13 on:** August 23, 2010, 02:37:03 PM »

Quote from: salat on August 23, 2010, 02:23:35 PM

Quote from: Quantum Dude on August 22, 2010, 10:54:07 PM
Quote from: salat on August 22, 2010, 10:47:13 PM

The ssri's are real killers of your sex drive because they boost seretonin too much, you want more dopamine for sex.

Thats highly theoretical and surely does not apply to everyone.

Which part is highly theoretical? The SSRI causing sexual problems or the dopamine involved in sexual arousal?

I'm sure nothing applies to everyone.

I read a lot of pubmed and my mind gets boggled at the conclusions they reach from making poor mice drown. I don't always do a good job of questioning what I read - still a bit programmed to believe scientists. They always sound so sure about their pronouncements. And I have a really horrible time trying to remember where I read what - even if I save it - I got literally gigabytes of saved stuff on my hard drive and not much in the way of organization and my house is littered with papers. I'm retiring October (early I'm only 50) and maybe I can get my private wiki up to start doing a better job of tracking this stuff. I get hyperfocused and on a trail of information - form hypothesis and promptly forget how I got there - leaving the very real need to verify my facts undone.

I recall reading that you wanted the balance of seretonin to be low in comparison to dopamine for increasing sex drive.

My personal experience is SSRI's suck (was on Effexor for 10 years) and kill your ability to orgasm. As in can't even masterbate dead! Adderall is much more pro sex.

salat

The part about SSRI's and sex drive. And I meant personal not theoretical, sorry about being lost in translation

. Anyways, Im sure you must be getting laid much more than me Salat and therefore must know much more about all this

.

QD

Tsathoggua · « **Reply #14 on:** August 23, 2010, 03:50:54 PM »

I cannot imagine taking an alpha2 adrenoreceptor antagonist for pleasure enhancement, talk about jittery, anxiogenic, awful shit, and thats pretty much it.

Can cause really severe akathisia, which is so casually described in the literature as 'a sense of inner restlessness and inability to keep still', that doesn't even begin to describe it, wanting to move constantly so badly you feel like ripping your skin off and jumping out of the nearest window is more like it. I believe it may lower seizure threshhold too, whilst on mirtazepine, at a very low dose (it has some alpha2 adrenoreceptor antagonist activity), a fraction of the lowest dose, it induced severe akathisia in me, and intolerable anxiety, coupled with uncontrollable myoclonic jerking, yohimbine does the same.

Yohimbine is fucking horrible stuff, you wouldn't want to take a selective and damn potent noradrenergic release agent would you? chances are the answer is hell no, well A2 is the autoreceptor for the noradrenergic system, antagonism induces noradrenaline release, so whilst it doesn't reverse the transporter like amphetamines do, it does something pretty similar when all is said and done, there is absolutely zero DA action, just intense peripheral and central adrenergic activity, think tachycardia, piloerection, anxiety, BP increase, akathisia, drymouth and a mood that would have you stamping on the heads of small babies for crying while you were trying to curl up in misery and there you have yohimbine in a small, ugly little nutshell.

There is a reason why it is not a controlled substance.

salat · « **Reply #15 on:** August 23, 2010, 04:04:37 PM »

Quote from: Quantum Dude on August 23, 2010, 02:37:03 PM

Quote from: salat on August 23, 2010, 02:23:35 PM
Quote from: Quantum Dude on August 22, 2010, 10:54:07 PM
Quote from: salat on August 22, 2010, 10:47:13 PM

Find yourself a fellow geek and be surprised.

The ssri's are real killers of your sex drive because they boost seretonin too much, you want more dopamine for sex.

Thats highly theoretical and surely does not apply to everyone.

Which part is highly theoretical? The SSRI causing sexual problems or the dopamine involved in sexual arousal?

I'm sure nothing applies to everyone.

I read a lot of pubmed and my mind gets boggled at the conclusions they reach from making poor mice drown. I don't always do a good job of questioning what I read - still a bit programmed to believe scientists. They always sound so sure about their pronouncements. And I have a really horrible time trying to remember where I read what - even if I save it - I got literally gigabytes of saved stuff on my hard drive and not much in the way of organization and my house is littered with papers. I'm retiring October (early I'm only 50) and maybe I can get my private wiki up to start doing a better job of tracking this stuff. I get hyperfocused and on a trail of information - form hypothesis and promptly forget how I got there - leaving the very real need to verify my facts undone.

I recall reading that you wanted the balance of seretonin to be low in comparison to dopamine for increasing sex drive.

My personal experience is SSRI's suck (was on Effexor for 10 years) and kill your ability to orgasm. As in can't even masterbate dead! Adderall is much more pro sex.

salat

The part about SSRI's and sex drive. And I meant personal not theoretical, sorry about being lost in translation . Anyways, Im sure you must be getting laid much more than me Salat and therefore must know much more about all this .

QD

embezzler · « **Reply #16 on:** August 23, 2010, 08:23:44 PM »

Quote

Catuaba
There are several trees used to produce catuaba - I use Trichilia catigua but want to try the Erythroxylum catuaba. I just haven't been able to locate it in cut/sifted form. I prefer to grind it at cooking time - more options chemistry wise. I soxhlet it with EtOH or vodka and then evap off the solvent.

Hey salat can you go a little into the effects of this one?

salat · « **Reply #17 on:** August 23, 2010, 11:59:20 PM »

The catuaba is a vasodilator - there's a slight increase in heart rate as your blood rushes to your skin and sexual organs. Touch is feels really good and tingly after this happens. Your sexual organs (male or female) get engorged with blood making them more sensitive to touch. You get tingles up your spine and neck sometimes.

I'm not good at recounting the technical details of it. I've uploaded some of the research I have done on it. I feel sorry for lab rats. If there's any justice in the world George Bush will be reincarnated as one!!

salat

jboogie · « **Reply #18 on:** August 26, 2010, 09:59:07 PM »

anyone ever try whippets when your cumming?

its like getting choked out kinda, but a little safer. you gotta time it right, but the overall effect is pretty nice...

dig the thread title by the way, nice play...

Sedit · « **Reply #19 on:** August 27, 2010, 02:48:09 AM »

Sounds kind of cool but the timing would be a boner killer for me. It sounds as the effects would be just like viagra except thats in a sence time released NO₂

Author Topic: The Pharma Sutra (Read 159 times)

embezzler

The Pharma Sutra

Quantum Dude

Re: The Pharma Sutra

Vesp

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embezzler

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Quantum Dude

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Satan

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Sedit

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salat

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Quantum Dude

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Vanadium

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Vesp

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Tsathoggua

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salat

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Quantum Dude

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Tsathoggua

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salat

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embezzler

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salat

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jboogie

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Sedit

Re: The Pharma Sutra