Author Topic: Phenprobamate to Methamphetamine  (Read 105 times)

solidstone

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Phenprobamate to Methamphetamine
« on: October 25, 2010, 03:48:41 PM »
 Phenprobamate, is a cheap and readily available muscle relaxant.

A saponification reaction should yield phenyl 3-propanol.  A dehydration reaction with say sulfuric acid should yield phenyl 3-propene.  Addition with HBr should yield phenyl 2-bromo propane, which is easily converted to phenyl 2 propanol.  From P2P the rest is history.
« Last Edit: October 25, 2010, 03:57:54 PM by solidstone »

Enkidu

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Re: Phenprobamate to Methamphetamine
« Reply #1 on: October 25, 2010, 06:15:20 PM »
I prefer discussions such as this to be centered around chemistry as opposed to precursors. Your post should detail each step of your proposed synthesis and include a few references. In other words, the post should be about the synthesis of allylbenzene (or 3-phenylpropene. Your phenyl 3-propene nomenclature is incorrect.) from 3-phenylpropanol. No one who wants to make phenylpropan-2-one needs to be told that he or she can prepare it from allylbenzene.

If you want to mention, as a side note, that 3-phenylpropanol can be prepared from the hydrolysis of Phenprobamate, you have my permission; however, the very idea of beginning with an anxiolytic drug that must be purchased, probably from an online pharmacy, is absurd. 3-phenylpropanol can be purchased without suspicion from a variety of sources. The only reason that anyone cares about urinary incontinence in dogs is that the medicine used during treatment is closer to the desired product, namely 4-MAR.

If you want to repost this topic, include a reference for the dehydration of a primary alcohol with sulfuric acid.
« Last Edit: July 13, 2011, 10:43:56 AM by Enkidu »