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Author Topic: Your thoughts on (substituted) amonium salts? Share them in here!  (Read 86 times)

guyp

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Your thoughts on (substituted) amonium salts? Share them in here!
« on: February 25, 2011, 04:28:13 AM »
A lot of people place too much concern on what mercury salts to use in a reductive amination. I think more thought should be given to what ammonium salts are used instead.

So what do you think?:

Ammonium Acetate vs Ammonium Chloride (and why?)

Methylamine HCl or Acetate or Sulfate or Nitrate. (and why?)

Tartarate, salicylate, (penta)borate, silicate ....

Theres a million of 'em!

Easier workup, smoother reaction, higher yields, lowered toxicity, reduced byproducts ...

or even plain old superstition.

Which salts do you prefer and why?

« Last Edit: February 25, 2011, 04:34:07 AM by guyp »

meme

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Re: Your thoughts on (substituted) amonium salts? Share them in here!
« Reply #1 on: February 25, 2011, 04:40:37 AM »
I was really wanting to talk about superacid salts of tertiary ammonia compounds, like tetraalkylammonium triflate.  They are sexy ionic liquids! When a superacid and a PTC fall in love, eh?  But I see I off topic a bit here, so I am heading back to lurkville.
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